Ben Halima A, Ibn Elhadj Z, Essmat W, Léfi A, Kammoun I, Zouaoui W, Marrakchi S, Chine S, Gargouri S, Keskes H, Kachboura S
Service de Cardiologie, Hôpital Abderrahmen Mami, 2080 Ariana, Tunisie.
J Mal Vasc. 2006 May;31(2):93-7. doi: 10.1016/s0398-0499(06)76526-x.
The incidence of tertiary syphilis has declined in recent years owing to the early recognition of the disease and use of antibiotics. As a result, syphilitic aortic aneurysms are rarely encountered nowadays. We report the case of a 65 years old man, who was admitted to our hospital in June 2004 for dyspnea, cough and chest discomfort. On physical examination, blood pressure was 130/80 mmHg with no significant laterality, pulse rate was 70 per minute and there was a decrease of breath sounds over the right lung. Laboratory findings revealed a slight elevation of the erythrocyte sedimentation rate. Serological studies for syphilis showed a positive venereal disease laboratory test (VDRL) at 1/32 and a positive Treponema pallidum hemagglutination test (TPHA) at 1/2560. The chest radiography showed a right para cardiac opacity measuring 16 x 12 cm. Fiber optic bronchoscopy showed an extrinsic compression of the right upper lobar bronchus. Gadolinium-enhanced magnetic resonance angiography and 16 multidetector-row spiral computed aortography showed a huge partially thrombosed saccular aneurysm of the ascending aorta measuring 132 mm in diameter. The circulating lumen measured 53 mm in its largest diameter. This aneurysm involved the innominate artery. There was no other arterial involvement. The patient was given a three week course of intravenous penicillin followed by a successful surgical procedure in September 2004 with ascending aortic replacement and innominate artery reimplantation. This case illustrates well a formerly common, but now extremely rare disease.
近年来,由于对梅毒的早期识别和抗生素的使用,三期梅毒的发病率有所下降。因此,如今梅毒主动脉瘤已很少见。我们报告一例65岁男性病例,该患者于2004年6月因呼吸困难、咳嗽和胸部不适入院。体格检查时,血压为130/80 mmHg,无明显双侧差异,脉搏率为每分钟70次,右肺呼吸音减弱。实验室检查结果显示红细胞沉降率略有升高。梅毒血清学检查显示性病研究实验室试验(VDRL)为1/32阳性,梅毒螺旋体血凝试验(TPHA)为1/2560阳性。胸部X线片显示右心旁有一16×12 cm的致密影。纤维支气管镜检查显示右上叶支气管有外压性改变。钆增强磁共振血管造影和16排螺旋计算机主动脉造影显示升主动脉有一个巨大的部分血栓形成的囊状动脉瘤,直径为132 mm。循环腔最大直径为53 mm。该动脉瘤累及无名动脉。无其他动脉受累。患者接受了为期三周的静脉青霉素治疗,随后于2004年9月成功进行了手术,行升主动脉置换和无名动脉再植术。该病例很好地说明了一种以前常见但现在极为罕见的疾病。