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[18F-FDG PET/CT在前列腺癌中的技术局限性]

[Technical limits of PET/CT with 18FDG in prostate cancer].

作者信息

von Mallek D, Backhaus B, Müller S C, Matthies A, Palmedo H, Jaeger U, Biersack H-J, Reinhardt M

机构信息

Klinik und Poliklinik für Nuklearmedizin, Universität Bonn, Bonn.

出版信息

Aktuelle Urol. 2006 May;37(3):218-21. doi: 10.1055/s-2006-932129.

DOI:10.1055/s-2006-932129
PMID:16733826
Abstract

There is increasing evidence that (18)FDG-PET is not useful for the imaging of primary prostate cancer. The aim of this examination was to prove whether or not these poor results are due to technical deficiencies of the examination method like older image reconstruction techniques, extensive (18)FDG-tracer activity in the bladder or improper contrast staining of the rectum. We examined three patients with primary prostate cancer using a modern combined PET/CT system, continuous irrigation of the bladder and an air-inflated rectal balloon catheter. PET/CT images show an exact depiction of both the prostate and all surrounding anatomic structures but no enhanced uptake of radiotracer in the tumour. Therefore, the mentioned poor results of (18)FDG-PET seem not to be due to technical deficiencies.

摘要

越来越多的证据表明,(18)氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)对原发性前列腺癌的成像并无用处。本次检查的目的是证明这些不佳结果是否归因于检查方法的技术缺陷,如陈旧的图像重建技术、膀胱内大量的(18)FDG示踪剂活性或直肠的对比染色不当。我们使用现代的PET/CT联合系统、膀胱持续冲洗以及充气的直肠球囊导管对三名原发性前列腺癌患者进行了检查。PET/CT图像精确显示了前列腺及所有周围的解剖结构,但肿瘤内并未出现放射性示踪剂摄取增强。因此,(18)FDG-PET上述的不佳结果似乎并非由于技术缺陷。

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