Peters F T M, Kleibeuker J H
Universitair Medisch Centrum Groningen, afd. Maag-, Darm- en Leverziekten, Groningen.
Ned Tijdschr Geneeskd. 2006 May 13;150(19):1059-64.
Gastro-oesophageal reflux disease is a chronic disorder. The most important therapeutic measure is long-term pharmacological acid inhibition. Anti-reflux surgery plays a role in cases where pharmacological treatment fails. A new development is endoluminal treatment for reflux disorders. The various methods used are based on one of the following principles: radiofrequency ablation, gastroplication and implantation of a bulking agent. Short-term results with endoluminal treatment are not very positive and longer-term results have been disappointing so far. Results from randomised studies are still largely unavailable. Longer follow-up and controlled randomised studies are needed before a well-founded judgment can be made regarding the place of endoluminal treatment in the therapeutic armamentarium.
胃食管反流病是一种慢性疾病。最重要的治疗措施是长期药物抑制胃酸。抗反流手术在药物治疗失败的情况下发挥作用。一种新的进展是针对反流性疾病的腔内治疗。所使用的各种方法基于以下原则之一：射频消融、胃折叠术和植入填充剂。腔内治疗的短期结果不太乐观，迄今为止长期结果也令人失望。随机研究的结果在很大程度上仍然不可得。在对腔内治疗在治疗手段中的地位做出有充分依据的判断之前，需要更长时间的随访和对照随机研究。
