Nielsen Paul J, Hafdahl Adam R, Conn Vicki S, Lemaster Joseph W, Brown Sharon A
Biochemistry Department, University of Missouri, Columbia, MO, United States.
Diabetes Res Clin Pract. 2006 Nov;74(2):111-20. doi: 10.1016/j.diabres.2006.03.033. Epub 2006 Jun 2.
This review applied meta-analytic procedures to integrate primary research that examined exercise fitness outcomes among adults with type 1 or type 2 diabetes. We used extensive literature searching strategies to locate published and unpublished intervention studies that tested exercise interventions. We conducted meta-analytic procedures using both fixed- and random-effects models. Analyses were conducted separately for type 1 and type 2 diabetes and separately for two-group and single-group data under two assumptions about pre-post fitness outcomes association: no association and a strong positive association (0.80). Codable data were extracted from 35 reports with 1074 subjects. The type 1 diabetes overall weighted mean effect size for two-group comparisons was 0.65. For treatment group pretest versus post-test, the effect was 0.62. The effect size among adults with type 2 diabetes for two-group comparisons was 0.35. The treatment group pretest versus post-test comparison effect was 0.37. Effect sizes among control group participants were not statistically different from 0. For type 2 diabetes two-group comparisons, larger effect sizes were associated with exercise prescription, fitness testing, supervised exercise, group sessions, and recommendations for longer duration exercise sessions. HbA1c, age, body mass index, and gender distribution were unrelated to fitness outcomes.
本综述应用荟萃分析方法，整合了针对1型或2型糖尿病成年人运动健身效果的原发性研究。我们采用广泛的文献检索策略，查找已发表和未发表的测试运动干预措施的干预性研究。我们使用固定效应模型和随机效应模型进行荟萃分析。针对1型和2型糖尿病，以及在关于前后健身效果关联的两个假设（无关联和强正相关（0.80））下，分别对两组和单组数据进行分析。从35份报告中提取了可编码数据，涉及1074名受试者。两组比较中，1型糖尿病的总体加权平均效应量为0.65。治疗组前测与后测的效应量为0.62。两组比较中，2型糖尿病成年人的效应量为0.35。治疗组前测与后测比较的效应量为0.37。对照组参与者的效应量与0无统计学差异。对于2型糖尿病两组比较，较大的效应量与运动处方、体能测试、有监督的运动、小组课程以及更长运动时长的建议相关。糖化血红蛋白、年龄、体重指数和性别分布与健身效果无关。
