de Miguel Mendieta E, Cobo Ibáñez T, Usón Jaeger J, Bonilla Hernán G, Martín Mola E
Department of Rheumatology, Hospital Universitario La Paz, Madrid, Spain.
Osteoarthritis Cartilage. 2006 Jun;14(6):540-4. doi: 10.1016/j.joca.2005.12.012.
To determine clinical and sonographic factors associated with painful episodes in patients with knee osteoarthritis (OA).
In this cross-sectional controlled study, patients with primary knee OA (ACR criteria) were prospectively placed into two groups. Group A: 81 patients with knee pain during physical activity >or=30 mm in visual analogue scale (VAS) for pain for at least 48 h prior to inclusion; Group B: 20 patients without knee pain from at least 1 month prior to inclusion. Clinical parameters, knee radiographic and ultrasonographic findings were collected. The sonographic study assessed joint effusion in the suprapatellar pouch, infrapatellar superficial and deep bursitis, meniscal lesions, anserine tendinobursitis, and Baker's cyst.
Group A patients tended to be older and heavier women than group B (P<0.05). The most frequent radiographic stage was III (57%) in group A, and I (35%) and II (35%) in group B, showing differences in the distribution of each radiographic stage (P<0.005). The most frequent ultrasonographic finding in group A was suprapatellar effusion (79%), and in group B it was meniscal lesions (40%). Ultrasonographic findings showed in group A a significant increase of suprapatellar effusion (P<0.001) and a tendency towards an increase of Baker's cyst (P=0.06). Suprapatellar effusion, Baker's cyst, and body mass index (BMI) were the factors associated with the appearance of pain after the logistic regression analysis.
Suprapatellar effusion, Baker's cyst, and higher BMI are more frequent and seem to be risk factors of painful flare in OA of the knee.
确定与膝关节骨关节炎(OA)患者疼痛发作相关的临床和超声因素。
在这项横断面对照研究中,将原发性膝关节OA(美国风湿病学会标准)患者前瞻性地分为两组。A组:81例在纳入研究前至少48小时内,体育活动时膝关节疼痛视觉模拟评分(VAS)≥30mm;B组:20例自纳入研究前至少1个月起无膝关节疼痛。收集临床参数、膝关节X线和超声检查结果。超声检查评估髌上囊积液、髌下浅部和深部滑囊炎、半月板损伤、鹅足肌腱滑囊炎和腘窝囊肿。
A组患者往往比B组患者年龄更大、体重更重,且为女性(P<0.05)。A组最常见的X线分期为III期(57%),B组为I期(35%)和II期(35%),各X线分期分布存在差异(P<0.005)。A组最常见的超声检查结果是髌上囊积液(79%),B组是半月板损伤(40%)。超声检查结果显示,A组髌上囊积液显著增加(P<0.001),腘窝囊肿有增加趋势(P=0.06)。经逻辑回归分析,髌上囊积液、腘窝囊肿和体重指数(BMI)是与疼痛出现相关的因素。
髌上囊积液、腘窝囊肿和较高的BMI更为常见,似乎是膝关节OA疼痛发作的危险因素。