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弥漫性特发性骨肥厚症:吞咽困难、气道梗阻和发音障碍的罕见病因。

Diffuse idiopathic skeletal hyperostosis: a rare cause of Dysphagia, airway obstruction, and dysphonia.

作者信息

Nelson R Scott, Urquhart Andrew C, Faciszewski Thomas

机构信息

Department of General Surgery, Marshfield Clinic, Marshfield, WI, USA.

出版信息

J Am Coll Surg. 2006 Jun;202(6):938-42. doi: 10.1016/j.jamcollsurg.2006.02.030.

Abstract

BACKGROUND

We retrospectively query the clinical records of patients with cervical osteophytes to distinguish the clinical features of those presenting with symptomatic dysphagia and airway obstruction.

STUDY DESIGN

Retrospective review of all patients presenting over a 20-year period (1985 to 2005) with the diagnosis of cervical osteophytes and dysphagia with or without airway compromise. Two hundred thirty-four patients were identified at Marshfield Clinic between 1985 and 2005; 9 (3.8%) met criteria for inclusion.

RESULTS

Eight of nine patients presented with dysphagia. Three of nine patients presented with acute airway obstruction requiring intubation and tracheotomy. Osteophytes occurred at multiple levels, with C4, C5, and C6 being most commonly involved. Surgical decompression resulted in complete resolution of symptoms in four of five patients.

CONCLUSIONS

Although commonly found and usually asymptomatic in the older population, anterior cervical osteophytes can be a source of considerable morbidity and potential life-threatening airway obstruction. Recognizing this clinical entity is imperative in establishing a diagnosis and initiating appropriate treatment. Surgical decompression appears to be beneficial in relieving symptoms.

摘要

背景

我们回顾性查询颈椎骨赘患者的临床记录,以区分出现症状性吞咽困难和气道阻塞患者的临床特征。

研究设计

对20年间(1985年至2005年)诊断为颈椎骨赘且伴有或不伴有气道受累的吞咽困难的所有患者进行回顾性研究。1985年至2005年间在马什菲尔德诊所确定了234例患者;9例(3.8%)符合纳入标准。

结果

9例患者中有8例出现吞咽困难。9例患者中有3例出现急性气道阻塞,需要插管和气管切开术。骨赘发生在多个节段,其中C4、C5和C6最常受累。手术减压使5例患者中的4例症状完全缓解。

结论

虽然颈椎前缘骨赘在老年人群中常见且通常无症状,但可导致相当大的发病率和潜在的危及生命的气道阻塞。认识到这一临床实体对于确立诊断和启动适当治疗至关重要。手术减压似乎有助于缓解症状。

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