Sircar D, Ghosh B, Ghosh Alakendu, Haldar S
Institute of Postgraduate Medical Institute and Research (IPGME&R), Kolkata, India.
Indian Pediatr. 2006 May;43(5):429-33.
This study attempts to determine the clinical manifestations, severity and immunological features of JIA and its influence on growth and associated cardiac involvement in children below 16 years of age. This is a cross sectional study in a tertiary referral center on 50 consecutive children below the age of 16 years. Each patient was thoroughly examined and scored on Juvenile Arthritis Functional Assessment Scale. Relevant blood tests, cardiac and ophthalmic evaluation was done. Growth patterns were noted. There was an overall equal sex ratio, though there was a male preponderance in the systemic and oligoarthritis groups. Disturbance of growth frequently occurred in children suffering from JIA. Cardiac involvement should be looked for in cases of JIA. Significant number of cases of PSRA is diagnosed in children presenting with chronic arthritis.
本研究旨在确定16岁以下儿童幼年特发性关节炎(JIA)的临床表现、严重程度和免疫学特征,及其对生长发育的影响和相关的心脏受累情况。这是一项在三级转诊中心对50例连续的16岁以下儿童进行的横断面研究。对每位患者进行了全面检查,并根据幼年关节炎功能评估量表进行评分。进行了相关血液检查、心脏和眼科评估。记录生长模式。总体性别比例均衡,不过在全身型和少关节型组中男性占优势。JIA患儿经常出现生长发育障碍。JIA病例应注意排查心脏受累情况。在患有慢性关节炎的儿童中,相当数量的病例被诊断为持续性少关节炎(PSRA)。