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青少年特发性关节炎中的精神疾病发病率、压力源、影响及负担

Psychiatric morbidity, stressors, impact, and burden in juvenile idiopathic arthritis.

作者信息

Mullick Mohammad S I, Nahar Jhunu S, Haq Syed Atiqul

机构信息

Department of Psychiatry, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka 1000, Bangladesh.

出版信息

J Health Popul Nutr. 2005 Jun;23(2):142-9.

Abstract

Juvenile idiopathic arthritis (JIA) is a chronic painful disorder conceivably with adverse psychological sequelae that might influence the outcome of the disease and its treatment. This study was designed to detect the presence of psychiatric disorders and associated abnormal psychosocial situations among children and adolescents with JIA and to evaluate their impact on and burden for their caregivers. Forty subjects with JIA suffering for at least one year were included in the study. Forty age- and sex-matched healthy subjects were included as controls. Clinical psychiatric assessment was carried out blindly, and psychiatric disorders and stressors on abnormal psychosocial situation were assigned on the basis of ICD-10 clinical diagnoses of multiaxial classification of child and adolescent psychiatric disorders. Chronicity, distress, social impairment, and burden for others were rated with the impact supplement of the strengths and difficulties questionnaire (SDQ). Of the 40 cases of JIA, 24 were boys and 16 were girls aged 10-18 years, with a mean age of 13.25 years. The frequency of psychiatric disorders was 35% in the JIA and 12.5% in the control group (p<0.001). The long duration of illness was associated with a higher proportion of cases with psychiatric disorders. In the JIA group, the diagnoses in decreasing order were depressive disorder (15%), somatoform disorder (12.5%), adjustment disorder (5%), and mixed anxiety and depressive disorder (2.5%). Significantly higher stressors, perceived difficulties, distress, social impairment, and burden for caregivers were reported in the JIA group with psychiatric morbidity. The presence of psychiatric disorders was associated with substantial impairment of learning, peer relationship, and leisure activities. Early psychiatric intervention might increase the likelihood of satisfactory outcome of treatment in JIA.

摘要

青少年特发性关节炎(JIA)是一种慢性疼痛性疾病,可能伴有不良心理后遗症,这可能会影响疾病的转归及其治疗。本研究旨在检测JIA儿童和青少年中精神障碍的存在情况以及相关的异常心理社会状况,并评估其对照顾者的影响和负担。40例患JIA至少一年的受试者被纳入研究。40例年龄和性别匹配的健康受试者作为对照。进行了盲法临床精神评估,并根据儿童和青少年精神障碍多轴分类的ICD - 10临床诊断确定精神障碍和异常心理社会状况的应激源。使用优势与困难问卷(SDQ)的影响补充量表对慢性程度、痛苦程度、社会功能损害以及对他人的负担进行评分。40例JIA患者中,24例为男孩,16例为女孩,年龄在10 - 18岁之间,平均年龄为13.25岁。JIA组精神障碍的发生率为35%,对照组为12.5%(p<0.001)。病程较长与精神障碍病例的比例较高相关。在JIA组中,诊断按比例递减依次为抑郁症(15%)、躯体形式障碍(12.5%)、适应障碍(5%)和混合性焦虑抑郁障碍(2.5%)。报告显示,有精神疾病的JIA组在应激源、感知到的困难、痛苦、社会功能损害以及照顾者负担方面显著更高。精神障碍的存在与学习、同伴关系和休闲活动的严重损害相关。早期精神干预可能会增加JIA治疗获得满意结果的可能性。

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