Power Michael L, Zinberg Stanley, Schulkin Jay
Department of Research, American College of Obstetricians and Gynecologists, Washington, DC 20024, USA.
Menopause. 2006 May-Jun;13(3):434-41. doi: 10.1097/01.gme.0000185753.77704.65.
To examine the knowledge and prescribing practices of obstetrician-gynecologists regarding hormone therapy in light of the published evidence from the Women's Health Initiative study on combined estrogen + progestin.
A survey questionnaire was sent to 2,500 randomly selected Fellows of the American College of Obstetricians and Gynecologists in November of 2003; 705 surveys were returned. Of those, 644 reported their specialty as obstetrics and/or gynecology and those responses are reported.
A majority of physicians that completed their residency before 1995, both men and women, were not convinced by the WHI research results and disagreed with the decision to end the trial. Physicians that rated themselves very confident about their ability to interpret the scientific literature were more likely to be unconvinced by the results and to disagree with the decision to end the trial. In general, physicians that completed their residency more recently rated the benefits of hormone therapy lower and the risks higher. A majority of respondents (53.3%) reported that their prescribing practices were unlikely to change; however, 29.6% reported that they would be somewhat less likely and 9.5% dramatically less likely to prescribe hormone therapy. Physicians reported that their patients were less likely to request hormone therapy (91.8%) and were more likely to discontinue use (93.0%).
Physicians that have been in practice longer were more positive about the risks and benefits of HT, and were more skeptical about the recent research. The published data seem to have affected patient preferences and to have had some effect on physician prescribing practices.
根据妇女健康倡议(Women's Health Initiative)关于联合雌激素+孕激素的研究发表的证据,考察妇产科医生关于激素治疗的知识和处方习惯。
2003年11月向随机抽取的2500名美国妇产科医师协会会员发送调查问卷;共返回705份调查问卷。其中,644人报告其专业为妇产科,以下报告的是这些人的回复。
1995年之前完成住院医师培训的大多数医生,无论男女,都不相信妇女健康倡议研究的结果,不同意终止该试验的决定。那些认为自己对解读科学文献的能力非常有信心的医生更有可能不相信研究结果,不同意终止试验的决定。总体而言,最近完成住院医师培训的医生对激素治疗益处的评价较低,对风险的评价较高。大多数受访者(53.3%)报告称他们的处方习惯不太可能改变;然而,29.6%的人报告称他们开激素治疗处方的可能性会略有降低,9.5%的人报告称可能性会大幅降低。医生们报告称,他们的患者要求进行激素治疗的可能性较小(91.8%),且更有可能停药(93.0%)。
从业时间较长的医生对激素治疗的风险和益处更为乐观,对近期研究更为怀疑。已发表的数据似乎影响了患者的偏好,并对医生的处方习惯产生了一定影响。