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良性结节性甲状腺肿的甲状腺次全切除术:对残余甲状腺功能及超声表现的术后6个月研究

Subtotal thyroidectomy for benign multinodular goiter: a 6-month postoperative study of the remnant's function and sonographic aspect.

作者信息

Bakiri Fawzy, Hassaïm Menad, Bourouba Mohamed-Sadreddine

机构信息

Service d'Endocrinologie, Hôpital Bologhine, Bains-Romains, 16060 Algiers, Algeria.

出版信息

World J Surg. 2006 Jun;30(6):1096-9. doi: 10.1007/s00268-005-0570-3.

Abstract

BACKGROUND

The purpose was to evaluate the thyroid function after subtotal thyroidectomy.

METHODS

One hundred and nineteen patients operated on for multinodular benign goiter were included in this prospective study. Results of the surgical treatment were evaluated 6 months after operation by thyroid-stimulating hormone (TSH) assay and cervical echography.

RESULTS

Thyroid-stimulating hormone levels correlated inversely (r=-0.78) with the thyroid remnant volumes. Forty-seven patients presented with a hypoechoic aspect of the remnant. Isoechoic and hypoechoic remnant volumes were similar; however, 46 of the 47 patients with a hypoechoic remnant (97.9%) had TSH levels higher than 5 mU/l vs. 39 of the 72 patients (54.2%) with an isoechoic aspect. No predictive factor for the occurrence of this hypoechoic feature was found.

CONCLUSIONS

After sub-total thyroidectomy for benign multinodular goiter, the volume of the remnant is not the only determinant of the occurrence of postoperative hypothyroidism. The appearance of a hypoechoic aspect of the remnant is also a strong predictive factor for such an outcome. In this case the occurrence of hypothyroidism is quite constant whatever the volume of the thyroid remnant. Since this evolution toward a hypoechoic aspect of the remnant is unpredictable, our results are an additional argument in favor of total thyroidectomy for benign multinodular goiter.

摘要

背景

目的是评估甲状腺次全切除术后的甲状腺功能。

方法

本前瞻性研究纳入了119例因多结节性良性甲状腺肿接受手术的患者。术后6个月通过促甲状腺激素(TSH)测定和颈部超声检查评估手术治疗结果。

结果

促甲状腺激素水平与甲状腺残余体积呈负相关(r = -0.78)。47例患者的残余甲状腺呈现低回声表现。等回声和低回声的残余体积相似;然而,47例低回声残余患者中有46例(97.9%)的TSH水平高于5 mU/l,而72例等回声表现患者中有39例(54.2%)TSH水平高于5 mU/l。未发现这种低回声特征出现的预测因素。

结论

对于良性多结节性甲状腺肿行甲状腺次全切除术后,残余体积并非术后甲状腺功能减退发生的唯一决定因素。残余甲状腺出现低回声表现也是这种结果的一个有力预测因素。在这种情况下,无论甲状腺残余体积如何,甲状腺功能减退的发生都相当常见。由于残余甲状腺向低回声表现的演变不可预测,我们的结果进一步支持对良性多结节性甲状腺肿行甲状腺全切除术。

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