[精神药物对慢性缺血性心脏病患者的疗效比较]

[Comparative effectiveness of psychotropic drugs in patients with chronic ischemic heart disease].

作者信息

Zaĭtsev V P, Shubina T I, Rubanovich A I, Podinovskaia Ia A

出版信息

Klin Med (Mosk). 1991 Jan;69(1):58-61.

Abstract

As many as 348 courses of psychotropic and antianginal chemotherapy were performed for coronary disease confirmed angiographically. Hypochondriac patients were resistant to the drugs, depressive states and anxiety showed the best response. Tranquilizers and neuroleptic agents proved effective in anxiety, neuroleptics in cardiophobia and hypochondria, antidepressants in depression and asthenia. The addition of psychotropic drugs to antianginal therapy produced a positive effect on cardiac pain with antidepressants benefit ranking first, neuroleptics second and tranquilizers third. Being moderate and transient, treatment-related side effects did not cause the treatment discontinuation.

摘要

对经血管造影确诊为冠心病的患者进行了多达348个疗程的精神药物和抗心绞痛化疗。疑病症患者对药物有抗药性，抑郁状态和焦虑状态的反应最佳。镇静剂和抗精神病药物对焦虑有效，抗精神病药物对心脏恐怖症和疑病症有效，抗抑郁药对抑郁症和虚弱有效。在抗心绞痛治疗中加用精神药物对心脏疼痛产生了积极影响，其中抗抑郁药效果最佳，其次是抗精神病药物，镇静剂位列第三。治疗相关的副作用程度较轻且为一过性，未导致治疗中断。