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原位杂交揭示神经组织中mRNA的定位与调控

Localization and regulation of mRNAs in the nervous tissue as revealed by in situ hybridization.

作者信息

Kawata M, Yuri K, Sano Y

机构信息

Department of Anatomy, Kyoto Prefectural University of Medicine, Japan.

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991;98(1):41-50.

PMID:1673919
Abstract
  1. In situ hybridization histochemistry permits the study of specific mRNAs of neuropeptides, enzymes involved in the synthesis of neurotransmitters, receptors and proteins associated with glial cells in nervous tissue. 2. The central and peripheral nervous systems are composed of heterogeneous elements and specific regulatory mechanisms occur in specific cells. 3. This review will focus on the localization and regulation of different mRNAs in the nervous system from Drosophila to human, as revealed by in situ hybridization histochemistry.
摘要
  1. 原位杂交组织化学可用于研究神经肽的特定信使核糖核酸(mRNA)、参与神经递质合成的酶、受体以及神经组织中与神经胶质细胞相关的蛋白质。2. 中枢神经系统和外周神经系统由异质性成分组成,特定的调节机制存在于特定细胞中。3. 本综述将聚焦于通过原位杂交组织化学所揭示的从果蝇到人类神经系统中不同mRNA的定位与调节。

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1
Localization and regulation of mRNAs in the nervous tissue as revealed by in situ hybridization.原位杂交揭示神经组织中mRNA的定位与调控
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991;98(1):41-50.
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Expression of three drebrin isoforms in the developing nervous system.
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Cellular influences on RNA sorting in neurons and glia: an in situ hybridization histochemical study.细胞对神经元和神经胶质细胞中RNA分选的影响:一项原位杂交组织化学研究。
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Preprotachykinin messenger RNA detected by in situ hybridization in striatal neurons of the human brain.通过原位杂交在人类大脑纹状体神经元中检测到前速激肽原信使核糖核酸。
Brain Res. 1987 Apr 28;410(1):83-8. doi: 10.1016/s0006-8993(87)80024-0.
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The use of in situ hybridization histochemistry for the study of neuropeptide gene expression in the human brain.原位杂交组织化学在人脑神经肽基因表达研究中的应用。
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[Hybridization in situ: methodology and applications to the analysis of phenomena of gene expression in endocrine glands and the nervous system].[原位杂交:内分泌腺和神经系统基因表达现象分析的方法与应用]
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