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[结肠直肠癌的筛查与预防]

[Screening and prevention of carcinoma of the colon and rectum].

作者信息

Weber C

机构信息

Gastroenterologie Klinik Sonnenhof, Bern.

出版信息

Ther Umsch. 2006 May;63(5):333-7. doi: 10.1024/0040-5930.63.5.333.

DOI:10.1024/0040-5930.63.5.333
PMID:16739892
Abstract

Carcinoma of the colon and rectum is the third most frequent malignant disease in industrialised countries. Incidence and mortality of colon cancer can be effectively lowered by population screening. The individual risk status of the patient has to be assessed before the screening procedure. In people with an average risk screening should be performed after the 50th birthday. The choice of the applied procedure (endoscopic procedures or fecal occult blood test) depends on the individual situation of the patient. Complete colonoscopy has the highest sensitivity and specificity for the detection of adenomas or carcinomas and should therefore be offered first. Alternatively flexible sigmoidoscopy or repetitive testing for occult blood can be applied. Despite promising developments in the radiographic detection of colonic lesions, virtual colonoscopy cannot be recommended as a screening procedure.

摘要

在工业化国家,结肠直肠癌是第三大常见恶性疾病。通过人群筛查可有效降低结肠癌的发病率和死亡率。在进行筛查程序之前,必须评估患者的个体风险状况。对于平均风险人群,应在50岁生日之后进行筛查。所应用程序(内镜检查程序或粪便潜血试验)的选择取决于患者的个体情况。全结肠镜检查对腺瘤或癌的检测具有最高的敏感性和特异性,因此应首先采用。或者,也可应用乙状结肠镜检查或反复进行潜血检测。尽管在结肠病变的放射学检测方面有了令人鼓舞的进展,但虚拟结肠镜检查不能作为一种筛查程序推荐。

相似文献

1
[Screening and prevention of carcinoma of the colon and rectum].[结肠直肠癌的筛查与预防]
Ther Umsch. 2006 May;63(5):333-7. doi: 10.1024/0040-5930.63.5.333.
2
Colorectal cancer screening: new opportunities.结直肠癌筛查:新机遇。
Surg Oncol Clin N Am. 1999 Oct;8(4):673-91, vi-vii.
3
One-time screening for colorectal cancer with combined fecal occult-blood testing and examination of the distal colon.采用粪便潜血联合检测及远端结肠检查进行一次性结直肠癌筛查。
N Engl J Med. 2001 Aug 23;345(8):555-60. doi: 10.1056/NEJMoa010328.
4
Many participants in fecal occult blood test population screening have a higher-than-average risk for colorectal cancer.许多参与粪便潜血试验人群筛查的人患结直肠癌的风险高于平均水平。
Eur J Gastroenterol Hepatol. 2006 Oct;18(10):1079-83. doi: 10.1097/01.meg.0000231754.35340.fa.
5
Colorectal cancer screening in average risk individuals.一般风险个体的结直肠癌筛查
Cancer Causes Control. 2005 Mar;16(2):171-88. doi: 10.1007/s10552-004-4027-z.
6
Cost-effectiveness of colon cancer screening.结肠癌筛查的成本效益
Am J Gastroenterol. 1991 Dec;86(12):1789-94.
7
How to screen for colon cancer.如何筛查结肠癌。
Annu Rev Med. 1998;49:163-72. doi: 10.1146/annurev.med.49.1.163.
8
The relative value of fecal occult blood tests and flexible sigmoidoscopy in screening for large bowel neoplasia.粪便潜血试验和乙状结肠镜检查在筛查大肠肿瘤中的相对价值。
Cancer. 1987 Nov 15;60(10):2553-8. doi: 10.1002/1097-0142(19871115)60:10<2553::aid-cncr2820601034>3.0.co;2-s.
9
[Results of Hemoccult screening of 45- to 65-year-old residents of the town of Ada with the goal of early detection of malignant neoplasms of the colon and rectum].
Med Pregl. 1985;38(1-2):77-81.
10
Colon cancer screening. Sigmoidoscopy or colonoscopy.结肠癌筛查。乙状结肠镜检查或结肠镜检查。
Gastrointest Endosc Clin N Am. 1997 Jul;7(3):365-86.