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参与波兰国家卒中预防与治疗登记处的各中心的急性缺血性卒中治疗与预后情况。

Acute ischemic stroke care and outcome in centers participating in the Polish National Stroke Prevention and Treatment Registry.

作者信息

Niewada Maciej, Skowrońska Marta, Ryglewicz Danuta, Kamiński Bogumił, Członkowska Anna

机构信息

Department of Clinical and Experimental Pharmacology, Warsaw Medical University, Poland.

出版信息

Stroke. 2006 Jul;37(7):1837-43. doi: 10.1161/01.STR.0000226992.39847.ef. Epub 2006 Jun 1.

Abstract

BACKGROUND AND PURPOSE

Significant intercenter variability in quality of care and stroke outcomes was found in many countries. The aim of the study was to compare the acute ischemic stroke care and outcomes in centers participating in the Polish National Stroke Prevention and Treatment Registry.

METHODS

The World Health Organization Stepwise Approach to Stroke Surveillance-based questionnaire was used to collect data on patients admitted to participating centers between December 1, 2001, and July 31, 2002. To ensure data quality, only centers reporting representative sample of patients were analyzed. Ischemic stroke patient characteristics, in-hospital care, and early outcomes (adjusted for case mix) were compared for participating centers.

RESULTS

There were 26 of 48 centers that met inclusion criteria, with a total of 8736 patients (52% women; mean age 71 years, with a range among institutions from 68 to 75 years). Significant differences between centers were observed for distribution of risk factors and in-hospital care. The rates for death and poor outcome (defined as a Rankin score > or =3 or death) ranged from 8.0% to 31.8% and from 44.2% to 74.7%, respectively. After adjusting for case mix, the death or poor outcome prognoses remained significantly different between centers.

CONCLUSIONS

The observed significant differences between Polish stroke centers indicate the need for improvement of patient education, effective stroke risk factor control, and standardized in-hospital care.

摘要

背景与目的

许多国家发现不同医疗中心在医疗质量和卒中结局方面存在显著差异。本研究旨在比较参与波兰国家卒中预防与治疗登记处的各中心对急性缺血性卒中的治疗情况及结局。

方法

采用基于世界卫生组织卒中监测逐步方法的问卷,收集2001年12月1日至2002年7月31日期间入住参与研究中心的患者数据。为确保数据质量,仅对报告具有代表性患者样本的中心进行分析。比较参与研究中心的缺血性卒中患者特征、住院治疗情况及早期结局(根据病例组合进行调整)。

结果

48个中心中有26个符合纳入标准,共有8736例患者(52%为女性;平均年龄71岁,各机构年龄范围为68至75岁)。各中心在危险因素分布和住院治疗方面存在显著差异。死亡率和不良结局发生率(定义为Rankin评分≥3或死亡)分别为8.0%至31.8%和44.2%至74.7%。在根据病例组合进行调整后,各中心之间的死亡或不良结局预后仍存在显著差异。

结论

波兰卒中中心之间观察到的显著差异表明,需要加强患者教育、有效控制卒中危险因素并实现标准化住院治疗。

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