Mujanovic Adnan, Smajlovic Dzevdet
Medical Faculty University of Tuzla Tuzla Bosnia and Herzegovina.
Department of Neurology University Clinical Center Tuzla Tuzla Bosnia and Herzegovina.
Health Sci Rep. 2021 Nov 29;4(4):e445. doi: 10.1002/hsr2.445. eCollection 2021 Dec.
Opacity of data on stroke for Bosnia and Herzegovina (B&H) is mainly due to the lack of a unified national stroke registry. This article aims to present updated epidemiological data on the etiology and risk factors for first-ever ischemic stroke in Tuzla Canton, B&H.
This retrospective hospital-based study included all first-ever ischemic stroke patients admitted between January 1, 2018 and December 31, 2018 at the Neurology Department, University Clinical Center Tuzla.
First-ever ischemic stroke was diagnosed in 739 patients. Leading risk factors were hypertension (94%), diabetes mellitus (40.7%), and dyslipidemia (38.8%). The most common stroke subtypes were atherothrombotic (36.8%), cardioembolic (21.9%), and stroke of undetermined etiologies (19.2%). Mean NIHSS score at discharge was 13 (IQR 2-16), and favorable patient outcome (mRs ≤2) was recorded in 26.4% patients. Men (aOR 0.39; 95% CI 0.24-0.64) and younger patients (aOR 0.96; 95% CI 0.93-0.98) had significantly higher probability of having a favorable outcome at discharge. Dyslipidemia could be considered as a predictive factor for patient outcome (aOR 0.66; 95% CI 0.43-1.00).
More than 92% of our patients had at least one modifiable risk factor, with hypertension and diabetes being at the forefront. One out of four patients had become functionally independent at discharge, while hospital mortality was lower than in other Eastern European countries. The overarching goal should be steered toward the development of a national stroke registry, which should be used as a reference for all further stroke management activities.
波斯尼亚和黑塞哥维那(波黑)缺乏统一的国家卒中登记系统,这主要导致该国卒中数据不透明。本文旨在呈现波黑图兹拉州首次缺血性卒中病因及危险因素的最新流行病学数据。
这项基于医院的回顾性研究纳入了2018年1月1日至2018年12月31日期间在图兹拉大学临床中心神经科住院的所有首次缺血性卒中患者。
共诊断出739例首次缺血性卒中患者。主要危险因素为高血压(94%)、糖尿病(40.7%)和血脂异常(38.8%)。最常见的卒中亚型为动脉粥样硬化血栓形成性(36.8%)、心源性栓塞性(21.9%)和病因不明性卒中(19.2%)。出院时美国国立卫生研究院卒中量表(NIHSS)平均评分为13分(四分位间距2 - 16),26.4%的患者获得良好的患者结局(改良Rankin量表评分≤2)。男性(调整后比值比[aOR]0.39;95%置信区间[CI]0.24 - 0.64)和年轻患者(aOR 0.96;95% CI 0.93 - 0.98)出院时获得良好结局的概率显著更高。血脂异常可被视为患者结局的预测因素(aOR 0.66;95% CI 0.43 - 1.00)。
我们的患者中超过92%至少有一个可改变的危险因素,其中高血压和糖尿病最为突出。四分之一的患者出院时功能独立,而医院死亡率低于其他东欧国家。总体目标应转向建立国家卒中登记系统,该系统应作为所有进一步卒中管理活动的参考。