Mendzheritskiĭ A M, Makletsova M G, Uskova N I, Choraian I O, Mikhaleva I I
Ukr Biokhim Zh (1978). 1991 Jan-Feb;63(1):34-7.
The influence of DSIP injection on the levels of neurotransmitters during hypokinetic stress was studied. It was shown that hypokinesia produced considerable changes in the levels of GABA glutamate, aspartate and homocarnosine. The injection of DSIP normalized the level of neurotransmitter amino acids. Administration of DSIP also reduced stress-induced changes in the activity of enzymes of GABA metabolism. Stress protective effect of DSIP was also demonstrated by normalising of the POL of lipids in brain.
研究了DSIP注射对运动功能减退应激期间神经递质水平的影响。结果表明，运动功能减退导致γ-氨基丁酸（GABA）、谷氨酸、天冬氨酸和高肌肽水平发生显著变化。DSIP注射使神经递质氨基酸水平恢复正常。给予DSIP还减少了应激诱导的GABA代谢酶活性变化。DSIP的应激保护作用还通过使大脑中脂质的磷脂水平正常化得到证实。
