文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Silva S V, Mercer J R

Department of Pathology, Ontario Veterinary College, University of Guelph, Canada.

Comp Biochem Physiol A Comp Physiol. 1991;98(3-4):551-8. doi: 10.1016/0300-9629(91)90445-i.

Experiments were conducted to examine the relationship between protein intake and protein degradation in the liver of cats. 2. The cats were fed either a low protein/high carbohydrate diet (LP) or a high protein diet devoid of carbohydrate (HP). 3. The potential proteolytic activity of the lysosomal vacuolar system in the liver was assessed by both indirect (osmotic fragility of hepatic lysosomes) and direct (stereological measurement of lysosomal volume) methods. 4. The results from both tests indicated a significantly lower autophagic activity of the lysosomal system in the LP fed animals than in the HP fed cats. 5. This suppression of lysosomal protein degradation may represent an important mechanism for the conservation of proteins by the cat when low protein diets are fed.

进行实验以研究猫肝脏中蛋白质摄入量与蛋白质降解之间的关系。2. 给猫喂食低蛋白/高碳水化合物饮食（LP）或不含碳水化合物的高蛋白饮食（HP）。3. 通过间接（肝溶酶体的渗透脆性）和直接（溶酶体体积的体视学测量）方法评估肝脏中溶酶体液泡系统的潜在蛋白水解活性。4. 两项测试的结果均表明，喂食LP的动物的溶酶体系统自噬活性明显低于喂食HP的猫。5. 溶酶体蛋白降解的这种抑制可能是猫在喂食低蛋白饮食时保存蛋白质的重要机制。

Silva S V, Mercer J R

Department of Pathology, Ontario Veterinary College, University of Guelph, Canada.

Comp Biochem Physiol A Comp Physiol. 1991;98(3-4):551-8. doi: 10.1016/0300-9629(91)90445-i.

Experiments were conducted to examine the relationship between protein intake and protein degradation in the liver of cats. 2. The cats were fed either a low protein/high carbohydrate diet (LP) or a high protein diet devoid of carbohydrate (HP). 3. The potential proteolytic activity of the lysosomal vacuolar system in the liver was assessed by both indirect (osmotic fragility of hepatic lysosomes) and direct (stereological measurement of lysosomal volume) methods. 4. The results from both tests indicated a significantly lower autophagic activity of the lysosomal system in the LP fed animals than in the HP fed cats. 5. This suppression of lysosomal protein degradation may represent an important mechanism for the conservation of proteins by the cat when low protein diets are fed.

进行实验以研究猫肝脏中蛋白质摄入量与蛋白质降解之间的关系。2. 给猫喂食低蛋白/高碳水化合物饮食（LP）或不含碳水化合物的高蛋白饮食（HP）。3. 通过间接（肝溶酶体的渗透脆性）和直接（溶酶体体积的体视学测量）方法评估肝脏中溶酶体液泡系统的潜在蛋白水解活性。4. 两项测试的结果均表明，喂食LP的动物的溶酶体系统自噬活性明显低于喂食HP的猫。5. 溶酶体蛋白降解的这种抑制可能是猫在喂食低蛋白饮食时保存蛋白质的重要机制。