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[新型线性酶免疫分析检测系统“INNO-Lia梅毒评分”的诊断效率研究结果]

[Results of study of the diagnostic efficiency of the new linear enzyme immunoassay test system "INNO-Lia Syphilis Score"].

作者信息

Frigo N V, Rotanov S V, Nesterenko V G, Lovenetskiĭ A N, Dudareva L A

出版信息

Klin Lab Diagn. 2006 Mar(3):36-41.

PMID:16749489
Abstract

A comparative study of 224 serum samples certified in different serological tests for syphilis has established the high diagnostic effectiveness of the new linear enzyme immunoassay test system (immune blotting assay "Improved INNO-Lia Syphilis ("IMMO-Lia Syphilis Score")) (Immunogenetics, Gent, Belgium). The assay showed a 100% sensitivity and 98% specificity; the reproducibility of positive and negative results was 100%. It is proposed to use the test system in the laboratories engaged in the expert diagnosis of syphilis as an additional or alternative Treponema pallidum immobilization test and immunofluorescence test supporting the assay of serum or plasma samples for this infection, which has yielded positive results on screening.

摘要

一项对224份经不同梅毒血清学检测认证的血清样本的比较研究,证实了新型线性酶免疫分析检测系统(免疫印迹分析“改进的INNO-Lia梅毒检测(“IMMO-Lia梅毒评分”)”)(免疫遗传学公司,根特,比利时)具有较高的诊断效能。该检测方法显示出100%的敏感性和98%的特异性;阳性和阴性结果的重现性均为100%。建议在从事梅毒专家诊断的实验室中使用该检测系统,作为梅毒螺旋体固定试验和免疫荧光试验的补充或替代方法,以辅助对筛查结果呈阳性的血清或血浆样本进行该感染的检测。

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