Saetta J P, March S, Gaunt M E, Quinton D N
Emergency Department, Leicester Royal Infirmary, Infirmary Close.
J R Soc Med. 1991 May;84(5):274-6. doi: 10.1177/014107689108400510.
A prospective, randomized, single-blind study was carried out to determine whether gastric content is forced into the small bowel when gastric-emptying procedures are employed in self-poisoned patients. They were asked to swallow barium-impregnated polythene pellets, immediately prior to either gastric lavage or ipecacuanha-induced emesis. A second group of patients, who did not require treatment, were used as controls. Sixty patients were recruited to the study. The data show a significant difference in the number of residual pellets in the small bowel of the treated group (n = 40), when compared with the control group (P less than 0.0001). There was no statistical difference in the number of pellets in the small bowel when the treated groups were compared with each other. In addition, the inefficiency of gastric-emptying procedures is highlighted; 58.5% of the total number of pellets ingested were retained in the gastrointestinal tract of the ipecacuanha-treated group, while 51.8% of total pellets ingested were retained in the gastric lavage-treated group.
开展了一项前瞻性、随机、单盲研究，以确定在对中毒患者采用洗胃程序时，胃内容物是否会被挤入小肠。要求他们在洗胃或吐根糖浆催吐之前立即吞下含钡聚乙烯颗粒。第二组不需要治疗的患者用作对照。该研究招募了60名患者。数据显示，与对照组相比，治疗组（n = 40）小肠中残留颗粒的数量有显著差异（P小于0.0001）。治疗组之间小肠中颗粒的数量没有统计学差异。此外，洗胃程序的无效性也很突出；吐根糖浆治疗组摄入的颗粒总数中有58.5%保留在胃肠道中，而洗胃治疗组摄入的颗粒总数中有51.8%保留在胃肠道中。
