Pearse Rupert M, Harrison David A, James Philip, Watson David, Hinds Charles, Rhodes Andrew, Grounds R Michael, Bennett E David
William Harvey Research Institute, Queen Mary's School of Medicine and Dentistry, London, UK.
Crit Care. 2006;10(3):R81. doi: 10.1186/cc4928. Epub 2006 Jun 2.
Little is known about mortality rates following general surgical procedures in the United Kingdom. Deaths are most common in the 'high-risk' surgical population consisting mainly of older patients, with coexisting medical disease, who undergo major surgery. Only limited data are presently available to describe this population. The aim of the present study was to estimate the size of the high-risk general surgical population and to describe the outcome and intensive care unit (ICU) resource use.
Data on inpatient general surgical procedures and ICU admissions in 94 National Health Service hospitals between January 1999 and October 2004 were extracted from the Intensive Care National Audit & Research Centre database and the CHKS database. High-risk surgical procedures were defined prospectively as those for which the mortality rate was 5% or greater.
There were 4,117,727 surgical procedures; 2,893,432 were elective (12,704 deaths; 0.44%) and 1,224,295 were emergencies (65,674 deaths; 5.4%). A high-risk population of 513,924 patients was identified (63,340 deaths; 12.3%), which accounted for 83.8% of deaths but for only 12.5% of procedures. This population had a prolonged hospital stay (median, 16 days; interquartile range, 9-29 days). There were 59,424 ICU admissions (11,398 deaths; 19%). Among admissions directly to the ICU following surgery, there were 31,633 elective admissions with 3,199 deaths (10.1%) and 24,764 emergency admissions with 7,084 deaths (28.6%). The ICU stays were short (median, 1.6 days; interquartile range, 0.8-3.7 days) but hospital admissions for those admitted to the ICU were prolonged (median, 16 days; interquartile range, 10-30 days). Among the ICU population, 40.8% of deaths occurred after the initial discharge from the ICU. The highest mortality rate (39%) occurred in the population admitted to the ICU following initial postoperative care on a standard ward.
A large high-risk surgical population accounts for 12.5% of surgical procedures but for more than 80% of deaths. Despite high mortality rates, fewer than 15% of these patients are admitted to the ICU.
在英国,关于普通外科手术后的死亡率,人们了解得很少。死亡在“高危”外科人群中最为常见,这类人群主要是患有并存疾病的老年患者,他们接受大手术。目前仅有有限的数据可用于描述这一人群。本研究的目的是估计高危普通外科人群的规模,并描述其结局以及重症监护病房(ICU)资源的使用情况。
从重症监护全国审计与研究中心数据库和CHKS数据库中提取了1999年1月至2004年10月期间94家国民健康服务医院的住院普通外科手术和ICU入院数据。高危外科手术被前瞻性地定义为死亡率达到或超过5%的手术。
共有4,117,727例外科手术;其中2,893,432例为择期手术(12,704例死亡;0.44%),1,224,295例为急诊手术(65,674例死亡;5.4%)。确定了513,924例高危患者(63,340例死亡;12.3%),这些患者占死亡总数的83.8%,但仅占手术总数的12.5%。这一人群住院时间延长(中位数为16天;四分位间距为9 - 29天)。共有59,424例患者入住ICU(11,398例死亡;19%)。在术后直接入住ICU 的患者中,有31,633例择期入院患者,3,199例死亡(10.1%),24,764例急诊入院患者,7,084例死亡(28.6%)。ICU住院时间较短(中位数为1.6天;四分位间距为0.8 - 3.7天),但入住ICU患者的住院时间延长(中位数为16天;四分位间距为10 - 30天)。在ICU人群中,40.8%的死亡发生在首次从ICU出院之后。最高死亡率(39%)出现在术后先在标准病房接受护理后入住ICU的人群中。
大量高危外科人群占外科手术总数的12.5%,但占死亡总数的80%以上。尽管死亡率很高,但这些患者中不到15%入住了ICU。