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流感与大流行威胁。

Influenza and the pandemic threat.

作者信息

Lee V J, Fernandez G G, Chen M I, Lye D, Leo Y S

机构信息

Department of Clinical Epidemiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.

出版信息

Singapore Med J. 2006 Jun;47(6):463-70.

Abstract

With the increasing concern of an imminent influenza pandemic, Singapore and many other countries have been developing preparedness plans. Influenza affects an estimated 20 percent of the population of Singapore annually, and local outbreaks can last for more than 12 weeks and occur at different periods of the year. The 1968 pandemic in Singapore had a clinical attack rate of about 20 percent and resulted in infections with fever that lasted up to five days. However, absenteeism from work due to seasonal influenza-like illnesses was estimated to be less than one day per person in Singapore. The next pandemic in Singapore is predicted to cause an average of 1,105 deaths and 3,338 hospitalisations, while a severe pandemic will cause more healthcare damage. Preventive strategies include national public health initiatives, vaccination, anti-viral therapy, and hygiene measures. To develop effective preparedness plans, it is important for healthcare workers to understand the disease's epidemiology, outcomes, and treatment and prevention strategies available.

摘要

随着对即将到来的流感大流行的关注度不断提高,新加坡和许多其他国家一直在制定防范计划。据估计,新加坡每年有20%的人口受到流感影响,本地疫情可能持续超过12周,且在一年中的不同时期发生。1968年新加坡的流感大流行临床发病率约为20%,导致发烧感染持续长达五天。然而,在新加坡,因季节性流感样疾病导致的旷工估计每人不到一天。预计新加坡的下一次大流行将平均导致1105人死亡和3338人住院,而严重的大流行将造成更大的医疗损害。预防策略包括国家公共卫生倡议、疫苗接种、抗病毒治疗和卫生措施。为制定有效的防范计划,医护人员了解该疾病的流行病学、后果以及现有的治疗和预防策略非常重要。

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