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经尿道微波热疗治疗良性前列腺增生:仍是一项挑战吗?

Transurethral microwave thermotherapy for the treatment of BPH: still a challenger?

作者信息

Herrmann T R W, Gross A J, Schultheiss D, Kaufmann P M, Jonas U, Burchardt M

机构信息

Department of Urology and Pediatric Urology, Medical School of Hannover (MHH), Carl Neuberg Street 1, 30625, Hannover, Germany.

出版信息

World J Urol. 2006 Sep;24(4):389-96. doi: 10.1007/s00345-006-0098-7. Epub 2006 Jun 3.

DOI:10.1007/s00345-006-0098-7
PMID:16752156
Abstract

Minimally invasive therapies for treatment of benign prostatic hyperplasia (BPH) compete with the gold standard transurethral resection of the prostate (TURP). Comparisons of efficacy and safety have broadened the knowledge of different treatment modalities. Concerns of quality of life such as unaltered sexual function as well as cost considerations drive the market to develop techniques of lower level invasiveness. Among the competitors the office based transurethral microwave thermotherapy (TUMT) provides the broadest scale of scientific data. Numerous manufacturers sell various modifications of this technology. According to different clinical studies TUMT proved to be an effective, safe, and durable therapy for the treatment of lower urinary tract symptoms (LUTS) secondary to BPH. However, TURP still holds the steadier long-term results and is more effective to reduce obstruction as well as other LUTS.

摘要

治疗良性前列腺增生(BPH)的微创疗法与前列腺电切术(TURP)这一金标准疗法相互竞争。疗效和安全性的比较拓宽了人们对不同治疗方式的认识。对性功能不受影响等生活质量问题的关注以及成本考量推动市场开发侵入性更低的技术。在众多竞争疗法中,门诊经尿道微波热疗(TUMT)拥有最广泛的科学数据。许多制造商销售该技术的各种改良版本。根据不同的临床研究,TUMT被证明是治疗BPH继发下尿路症状(LUTS)的一种有效、安全且持久的疗法。然而,TURP仍保持更稳定的长期效果,在减轻梗阻及其他LUTS方面更有效。

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引用本文的文献

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Transurethral Microwave Thermotherapy (TUMT) in the Treatment of Benign Prostatic Hyperplasia: A Preliminary Report.经尿道微波热疗(TUMT)治疗良性前列腺增生:初步报告。
Med Sci Monit. 2021 Jul 8;27:e931597. doi: 10.12659/MSM.931597.
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Various treatment options for benign prostatic hyperplasia: A current update.良性前列腺增生的各种治疗选择:最新进展
J Midlife Health. 2012 Jan;3(1):10-9. doi: 10.4103/0976-7800.98811.
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Phase 1 and 2 studies demonstrate the safety and efficacy of intraprostatic injection of PRX302 for the targeted treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.

本文引用的文献

1
Transurethral microwave thermotherapy: clinical results after 11 years of use.经尿道微波热疗:使用11年后的临床结果
J Endourol. 2005 Jul-Aug;19(6):730-3. doi: 10.1089/end.2005.19.730.
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Transurethral microwave thermotherapy vs transurethral resection for treating benign prostatic hyperplasia: a systematic review.经尿道微波热疗与经尿道前列腺切除术治疗良性前列腺增生的系统评价
BJU Int. 2004 Nov;94(7):1031-6. doi: 10.1111/j.1464-410X.2004.05099.x.
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EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines).
Ⅰ期和Ⅱ期研究表明,经直肠前列腺内注射 PRX302 治疗前列腺增生所致下尿路症状是安全有效的。
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Impact of oral anticoagulation on morbidity of transurethral resection of the prostate.口服抗凝药对经尿道前列腺切除术发病率的影响。
World J Urol. 2011 Apr;29(2):211-6. doi: 10.1007/s00345-010-0561-3. Epub 2010 Jun 25.
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Transurethral ultrasound applicators with dynamic multi-sector control for prostate thermal therapy: in vivo evaluation under MR guidance.用于前列腺热疗的具有动态多扇区控制功能的经尿道超声探头:在磁共振引导下的体内评估
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欧洲泌尿外科学会(EAU)2004年关于疑似良性前列腺梗阻的男性下尿路症状的评估、治疗及随访指南(BPH指南)
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Transurethral microwave thermotherapy for benign prostate hyperplasia: separating truth from marketing hype.
J Urol. 2004 Oct;172(4 Pt 1):1249-55. doi: 10.1097/01.ju.0000129967.30558.ca.
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The cost of feedback microwave thermotherapy compared with transurethral resection of the prostate for treating benign prostatic hyperplasia.反馈式微波热疗与经尿道前列腺切除术治疗良性前列腺增生的成本比较。
BJU Int. 2004 Mar;93(4):543-8. doi: 10.1111/j.1464-410x.2003.04689.x.
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Evaluation of microwave thermotherapy with histopathology, magnetic resonance imaging and temperature mapping.
J Urol. 2004 Feb;171(2 Pt 1):672-8. doi: 10.1097/01.ju.0000108136.41620.95.
7
Transurethral resection vs microwave thermotherapy of the prostate: a cost-consequences analysis.经尿道前列腺切除术与前列腺微波热疗:成本效益分析
BJU Int. 2003 Nov;92(7):713-8. doi: 10.1046/j.1464-410x.2003.04470.x.
8
Efficacy and safety of intraprostatic temperature-controlled microwave thermotherapy in patients with benign prostatic hyperplasia: results of a prospective, open-label, single-center study with 1-year follow-up.经直肠温控微波热疗治疗良性前列腺增生症的疗效和安全性:一项前瞻性、开放标签、单中心、为期1年随访研究的结果
J Endourol. 2003 Aug;17(6):425-30. doi: 10.1089/089277903767923236.
9
How do transurethral needle ablation of the prostate and transurethral microwave thermotherapy compare with transurethral prostatectomy?经尿道前列腺针刺消融术和经尿道微波热疗与经尿道前列腺切除术相比如何?
Curr Urol Rep. 2003 Aug;4(4):297-306. doi: 10.1007/s11934-003-0088-x.
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AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1: Diagnosis and treatment recommendations.美国泌尿外科学会良性前列腺增生管理指南(2003年)。第1章:诊断与治疗建议。
J Urol. 2003 Aug;170(2 Pt 1):530-47. doi: 10.1097/01.ju.0000078083.38675.79.