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经尿道微波热疗(TUMT)治疗良性前列腺增生:初步报告。

Transurethral Microwave Thermotherapy (TUMT) in the Treatment of Benign Prostatic Hyperplasia: A Preliminary Report.

机构信息

Department of Urology, Hospital of the Ministry of Internal Affairs and Administration, Szczecin, Poland.

Department of Normal and Clinical Anatomy, Pomeranian Medical University, Szczecin, Poland.

出版信息

Med Sci Monit. 2021 Jul 8;27:e931597. doi: 10.12659/MSM.931597.

DOI:10.12659/MSM.931597
PMID:34234095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8276617/
Abstract

BACKGROUND One treatment option for benign prostatic hyperplasia (BPH) is transurethral microwave thermotherapy (TUMT). Unfortunately, TUMT has been increasingly marginalized recently. The aim of this study was to evaluate erectile function and urinary symptoms in patients after TUMT for BPH and compare the results with those of patients on pharmacological treatment for BPH. MATERIAL AND METHODS The study group consisted of 840 patients with BPH treated with TUMT and a control group consisting of 1040 patients who underwent pharmacotherapy. Erectile dysfunction was evaluated using the International Index of Erectile Function-5 questionnaire and the Individual Postoperative Erectile Assessment (IPEA) questionnaire, which was created by the authors for this study. Urinary symptoms were evaluated using the International Prostate Symptom Score (IPSS) questionnaire. RESULTS More than 50% of all patients experienced an improvement in urinary symptoms after TUMT, compared with only approximately 30% in the control group. Differences in each of the IPSS symptom scales between the TUMT and control groups were statistically significant (P<0.031, P<0.041, and P<0.025 for mild, moderate, and severe symptoms, respectively). Improvement in erectile dysfunction after TUMT was also statistically significant (P<0.0001, P<0.0001, P<0.05 for mild, moderate, and severe erectile dysfunction, respectively). Based on the IPEA questionnaire, approximately 24% of the TUMT group reported significant improvement in erectile function, while a decrease in erectile function was reported in the control group. CONCLUSIONS TUMT may still be a valuable option in the treatment of BPH. TUMT may be especially suitable for patients who expect to improve urinary symptoms without decreasing erectile function.

摘要

背景

良性前列腺增生 (BPH) 的一种治疗选择是经尿道微波热疗 (TUMT)。不幸的是,TUMT 最近已逐渐被边缘化。本研究旨在评估 TUMT 治疗 BPH 后患者的勃起功能和尿症状,并将结果与接受 BPH 药物治疗的患者进行比较。

材料与方法

研究组由 840 例接受 TUMT 治疗的 BPH 患者组成,对照组由 1040 例接受药物治疗的患者组成。勃起功能障碍采用国际勃起功能指数-5 问卷和作者为此研究创建的个体术后勃起评估 (IPEA) 问卷进行评估。尿症状采用国际前列腺症状评分 (IPSS) 问卷进行评估。

结果

与对照组相比,超过 50%的患者 TUMT 治疗后尿症状得到改善,而对照组仅约 30%的患者如此。TUMT 和对照组之间每个 IPSS 症状量表的差异均具有统计学意义 (P<0.031、P<0.041 和 P<0.025,分别为轻度、中度和重度症状)。TUMT 后勃起功能障碍的改善也具有统计学意义 (P<0.0001、P<0.0001 和 P<0.05,分别为轻度、中度和重度勃起功能障碍)。根据 IPEA 问卷,TUMT 组约 24%的患者报告勃起功能显著改善,而对照组报告勃起功能下降。

结论

TUMT 可能仍然是 BPH 治疗的一种有价值的选择。TUMT 可能特别适合希望改善尿症状而不降低勃起功能的患者。

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