Borchardt S M, Polyak G, Dworkin M S
Division of Infectious Diseases, Illinois Department of Public Health, Chicago, IL 60601, USA.
Epidemiol Infect. 2007 Jan;135(1):11-6. doi: 10.1017/S0950268806006480. Epub 2006 Jun 6.
We describe parental attitude towards mass antimicrobial prophylaxis and adolescent booster vaccination to prevent pertussis. A survey was distributed to parents at a large suburban high school where an outbreak of pertussis was occurring. A total of 314 surveys were received among 450 distributed. If antimicrobial prophylaxis was recommended for all students and faculty as a method of controlling a pertussis outbreak in their child's school (i.e. mass antimicrobial prophylaxis), 40% of parents would have their child take the medication and 49% might have their child take the antibiotic but would first consult their child's physician. Having > or =2 children attend the high school (OR 2.2, 95% CI 1.10-4.59) and generally favouring immunizations (OR 1.7, 95% CI 0.99-2.87) were predictors of likely compliance with mass antimicrobial prophylaxis. These findings underscore the importance of communicating the rationale of public health intervention efforts to physicians in order to help ensure their success.
我们描述了父母对于大规模抗菌药物预防以及青少年百日咳加强疫苗接种的态度。在一所郊区大型高中爆发百日咳期间，我们向家长发放了调查问卷。共发放450份问卷，回收314份。如果为控制孩子所在学校的百日咳疫情，建议对所有学生和教职员工进行抗菌药物预防（即大规模抗菌药物预防），40%的家长会让孩子服药，49%的家长可能会让孩子服用抗生素，但会先咨询孩子的医生。家中有≥2个孩子在该高中上学（比值比2.2，95%可信区间1.10 - 4.59）以及总体上支持免疫接种（比值比1.7，95%可信区间0.99 - 2.87）是可能遵守大规模抗菌药物预防措施的预测因素。这些发现强调了向医生传达公共卫生干预措施基本原理的重要性，以帮助确保这些措施取得成功。
