Powell Timothy M, Tarter Thomas H
Division of Urology, Department of Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.
J Urol. 2006 Jul;176(1):96-8; discussion 99. doi: 10.1016/S0022-5347(06)00496-4.
We report on 4 patients who presented with nonpalpable testicular masses discovered on scrotal ultrasound, and offer treatment recommendations based on our experience and a review of the literature.
Four patients underwent intraoperative ultrasound guided localization and excisional biopsy of nonpalpable testicular parenchymal masses. Radical orchiectomy was performed in 2 patients because of testicular cancer. Patient age, clinical presentation, ultrasound results, frozen section and permanent pathology results are reported.
During a 3-year period 1,040 scrotal ultrasounds were performed for indications other than retroperitoneal mass at a single institution, and nonpalpable testicular parenchymal masses were discovered in 4 patients with an age range of 22 to 31 years. Testis mass size ranged from 5 to 6 mm in maximum diameter and serum tumor markers were negative in all patients. Frozen section pathology indicated benign lesions in all patients and permanent pathology revealed seminoma in 2 of the patients who underwent delayed radical orchiectomy. Permanent pathology of orchiectomy specimens did not reveal residual invasive tumor.
Intraoperative ultrasound guided localization and excisional biopsy is a reasonable treatment option for patients with nonpalpable incidental testicular masses. Excisional biopsy with margins that show normal testicular tissue is essential in testis sparing surgery and patients must be cautioned that final pathology may indicate the need for delayed radical orchiectomy.
我们报告4例经阴囊超声检查发现睾丸可触及肿块的患者,并根据我们的经验及文献复习给出治疗建议。
4例患者接受了术中超声引导下不可触及睾丸实质肿块的定位及切除活检。2例因睾丸癌行根治性睾丸切除术。报告了患者年龄、临床表现、超声结果、冰冻切片及永久病理结果。
在3年期间,某单一机构对1040例患者进行了除腹膜后肿块以外指征的阴囊超声检查,发现4例年龄在22至31岁之间的患者存在不可触及的睾丸实质肿块。睾丸肿块最大直径为5至6毫米,所有患者血清肿瘤标志物均为阴性。冰冻切片病理显示所有患者均为良性病变,2例接受延迟根治性睾丸切除术患者的永久病理显示为精原细胞瘤。睾丸切除标本的永久病理未发现残留浸润性肿瘤。
术中超声引导下定位及切除活检是不可触及的偶然性睾丸肿块患者的合理治疗选择。在保留睾丸手术中,切除边缘显示正常睾丸组织的活检至关重要,且必须告知患者最终病理可能提示需要延迟根治性睾丸切除术。