McMahon D R, Cain M P, Husmann D A, Kramer S A
Department of Urology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, 55905, USA.
J Urol. 1996 Apr;155(4):1411-3.
We evaluated the factors critical in achieving urinary medicine continence in patients with the exstrophy-epispadias complex.
A total of 51 patients with epispadias and 33 with classic bladder exstrophy underwent vesical neck reconstruction. Patient records were reviewed to identify factors associated with achievement of continence, including timing of bladder closure and urethroplasty, effect of bladder capacity before and after vesical reconstruction, and effect of enterocystoplasty.
Complete urinary continence was achieved in 42 of the 51 patients with epispadias (82%) and in 23 of the 33 with exstrophy (70%). Delayed bladder closure did not affect the ability to gain continence but increased the likelihood of subsequent enterocystoplasty (12 of 19 patients, 63%) compared to early bladder closure (5 of 14 patients, 36%).
Preliminary urethroplasty did not enhance urinary control or reduce the need for enterocystoplasty. Bladder capacity before vesical neck reconstruction did not predict the need for enterocystoplasty or ultimate continence status in individuals. Adequate bladder capacity after vesical neck reconstruction was an important determinant of urinary continence. Approximately half of the patients bladder exstrophy (17 of 33) required augmentation cystoplasty to achieve urinary continence.
我们评估了在膀胱外翻-尿道上裂复合畸形患者中实现尿失禁控制的关键因素。
共有51例尿道上裂患者和33例典型膀胱外翻患者接受了膀胱颈重建术。回顾患者记录以确定与实现尿失禁控制相关的因素,包括膀胱闭合和尿道成形术的时机、膀胱重建前后膀胱容量的影响以及肠膀胱扩大术的影响。
51例尿道上裂患者中有42例(82%)实现了完全尿失禁,33例膀胱外翻患者中有23例(70%)实现了完全尿失禁。延迟膀胱闭合并不影响获得尿失禁控制的能力,但与早期膀胱闭合(14例中的5例,36%)相比,增加了随后进行肠膀胱扩大术的可能性(19例中的12例,63%)。
初步尿道成形术并未增强尿控能力或减少肠膀胱扩大术的需求。膀胱颈重建术前的膀胱容量并不能预测个体是否需要进行肠膀胱扩大术或最终的尿失禁状态。膀胱颈重建术后足够的膀胱容量是尿失禁的一个重要决定因素。大约一半的膀胱外翻患者(33例中的17例)需要进行膀胱扩大成形术以实现尿失禁控制。