Császár Albert, Kékes Ede, Abel Tánja, Papp Renata, Kiss István, Balogh Sándor
Department of Medicine, National Medical Center, St. Imre Hospital, Budapest, Hungary.
Blood Press. 2006;15(2):101-6. doi: 10.1080/08037050600772284.
In recent years, metabolic syndrome (MS) became a distinct pathological entity. MS is positively associated with cardiovascular mortality. The prevalence of MS is high and a continuing increase is expected. For this reason, all attempts to prevent or manage MS by interventions are extremely important. The new set of definition by International Diabetes Federation (IDF) standardizes criteria for the diagnosis of MS and facilitates its recognition. In a large sample (n = 13 383) of outpatients visiting their general practitioners, we determined the prevalence of risk factors of MS according to the earlier Adult Treatment Panel (ATP) III and the new IDF criteria.
The age-standardized prevalence of MS was 14.9% in males and 8.6% in females (11.5% for all). The most prevalent factors were obesity (ATP III: 38.8% and IDF: 60%) and hypertriglyceridemia (34.1%). Hypertension dominated in men (28.7%), whereas in women obesity was the most prevalent factor (ATP III: 47.4% and IDF: 64%).
The prevalence of MS depends on applied definition. The new IDF criteria offer the possibility of focusing on the importance of different components. The real comparison of prevalence among special populations has to be based on age-standardized data and the use of the same components. In our study, the dominance of obesity, hypertension and hypertriglyceridemia appears to be the major detrimental factors. The 11.5% general prevalence of MS in Hungarians, which means a 25-30% value in the middle-aged population, needs an urgent preventive approach with lifestyle changes.
近年来，代谢综合征（MS）已成为一种独特的病理实体。MS与心血管疾病死亡率呈正相关。MS的患病率很高，且预计还会持续上升。因此，通过干预措施预防或管理MS的所有尝试都极为重要。国际糖尿病联盟（IDF）制定的新定义对MS的诊断标准进行了规范，便于其识别。在一个访问全科医生的大型门诊样本（n = 13383）中，我们根据早期的成人治疗小组（ATP）III和新的IDF标准确定了MS危险因素的患病率。
MS的年龄标准化患病率在男性中为14.9%，在女性中为8.6%（总体为11.5%）。最常见的因素是肥胖（ATP III：38.8%，IDF：60%）和高甘油三酯血症（34.1%）。高血压在男性中占主导（28.7%），而在女性中肥胖是最常见的因素（ATP III：47.4%，IDF：64%）。
MS的患病率取决于所采用的定义。新的IDF标准提供了关注不同组成部分重要性的可能性。特殊人群患病率的实际比较必须基于年龄标准化数据和相同组成部分的使用。在我们的研究中，肥胖、高血压和高甘油三酯血症的主导地位似乎是主要的有害因素。匈牙利人MS的总体患病率为11.5%，这意味着中年人群中的患病率为25% - 30%，需要通过改变生活方式采取紧急预防措施。
