Inokuchi Taku, Shincho Mayumi, Moriwaki Yuji, Ka Tsuneyoshi, Takahashi Sumio, Tsutsumi Zenta, Lin Yoshiaki, Hirota Seiichi, Yamamoto Tetsuya
Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.
Intern Med. 2006;45(9):641-7. doi: 10.2169/internalmedicine.45.1564. Epub 2006 Jun 1.
A 78-year-old man with a history of mycosis fungoides was referred for evaluation of a right adrenal mass. A physical examination showed the left cervical lymph node to be palpable, which was later shown to be caused by a diffuse large B-cell lymphoma. The patient was diagnosed with concurrent mycosis fungoides and a diffuse large B-cell lymphoma. Three courses of chemotherapy were performed, however, the patient died of advanced disease. Autopsy findings showed that the right adrenal and soft tissue masses had an identical B-cell origin. Although the exact mechanism remains unclear, the pathogenesis of this rare association is discussed.
一名78岁有蕈样肉芽肿病史的男性因右肾上腺肿块前来评估。体格检查发现左侧颈部淋巴结可触及,后来证实是由弥漫性大B细胞淋巴瘤引起的。该患者被诊断为同时患有蕈样肉芽肿和弥漫性大B细胞淋巴瘤。进行了三个疗程的化疗,然而,患者死于晚期疾病。尸检结果显示右肾上腺和软组织肿块有相同的B细胞起源。尽管确切机制尚不清楚,但对这种罕见关联的发病机制进行了讨论。