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[怀疑进展为蕈样肉芽肿的斑块状副银屑病伴颊部结外恶性B细胞淋巴瘤]

[Parapsoriasis en plaque suspected of progression to mycosis fungoides associated with extranodal malignant B cell lymphoma of the cheek].

作者信息

Onizuka T, Satou S, Koike M, Ishiyama T, Tomoyasu S, Tsuruoka N, Ohta H, Fujisawa R, Yamaguchi A, Tashiro T

机构信息

Department of Hematology, Showa University.

出版信息

Rinsho Ketsueki. 1993 Jun;34(6):723-7.

PMID:8366574
Abstract

A 59-year-old female, clinically diagnosed as having parapsoriasis en plaque for ten years, was referred on June 1991 to the Department of Oral Surgery in the Dental School of showa University with a complaint of painless swelling of the left malar area. The swelling was found to have been caused by a tumor. Since the excised tumor was suspected to be a malignant lymphoma, she was admitted to our hospital. The specimen was subsequently confirmed to be a malignant lymphoma of the diffuse large cell type according to the LSG classification, and was immunologically confirmed to be a B cell lymphoma. In addition, the excised skin was suspected of incipient mycosis fungoides. She was classified as having stage IE disease according to her bone marrow biopsy and other examinations. she was treated with combination of chemotherapy (CHOP) and radiation therapy. This subject was interesting because her tumor probably resulted from a parapsoriasis en plaque skin lesion.

摘要

一名59岁女性,临床诊断为斑块状副银屑病10年,于1991年6月因左侧颧骨区域无痛性肿胀就诊于昭和大学牙科学院口腔外科。发现肿胀是由肿瘤引起的。由于切除的肿瘤怀疑是恶性淋巴瘤,她被收治入院。随后,根据LSG分类,标本被确认为弥漫大细胞型恶性淋巴瘤,并经免疫检查确认为B细胞淋巴瘤。此外,切除的皮肤怀疑有蕈样肉芽肿早期病变。根据骨髓活检和其他检查,她被分类为IE期疾病。她接受了化疗(CHOP方案)和放射治疗相结合的治疗。该病例很有意思,因为她的肿瘤可能源于斑块状副银屑病皮肤病变。

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