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手术诱导减肥的长期健康和社会心理结果:未参加预定随访的患者的结果

Long-term health and psychosocial outcomes from surgically induced weight loss: results obtained in patients not attending protocolled follow-up visits.

作者信息

Mathus-Vliegen E M H

机构信息

EMH Mathus-Vliegen, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.

出版信息

Int J Obes (Lond). 2007 Feb;31(2):299-307. doi: 10.1038/sj.ijo.0803404. Epub 2006 Jun 6.

Abstract

OBJECTIVE

Obesity management is focused at weight loss to obtain health, psychological and social benefits. Outcomes from controlled trials, however, do not reflect the everyday routine practice. Therefore, we aimed to investigate the results from surgically induced weight loss in patients devoid of a protocol-wise follow-up, who were visited at home.

PATIENTS AND METHODS

Patients who underwent a vertical banded gastroplasty or a gastric bypass between 1980 and 1997 were eligible. Body weight and height were measured. Patients filled out questionnaires on health status (Nottingham Health Profile (NHP)), psychological symptoms (Symptom Check List (SCL-90-R)), personality traits (Dutch Personality Questionnaire (DPQ)) and eating behaviour (Dutch Eating Behaviour Questionnaire (DEBQ)).

RESULTS

Out of 451 operated patients the addresses of 313 subjects could be traced and 236 (75%) agreed to participate. They maintained a mean (s.d.) loss of 32.1 (22.6) kg and 45.2 (29.3) % of excess weight, 8.2 (4.5) years after the operation, about two-third of the largest weight loss they achieved after 17 months postoperatively. The NHP and SCL-90-R conformed to norm values in males except for energy, sleep and emotional reactions. Females differed from norm values in every aspect and even women achieving a BMI<30 kg/m(2) did not catch up to norm values. Weight loss was inversely related to physical immobility and pain. Personality traits (DPQ) showed a higher grievance and dominance and a lower rigidity and self-esteem compared to norm values. Females scored higher in inadequacy and lower in social inadequacy. Eating patterns (DEBQ) showed mainly emotional eating and restrained eating. Effect sizes of >/=0.8 s.d. were chosen to reflect the clinical relevance of statistically significant findings. Pain, disturbances in sleep, energy and mobility and emotional and restrained eating proved to be clinically relevant. In subjects operated >5 years ago, a higher sensitivity, a higher inadequacy and a lower social inadequacy were observed compared to more recently operated subjects. A more restrained eating pattern was related to an operation of recent date.

CONCLUSIONS

Surgically induced weight losses are satisfactory in the long-term, even in patients not attending a strict follow-up protocol. Health, psychological symptoms, personality traits and eating behaviour were related to weight loss and time lapse since the operation and did not return to reference normal-weight subject values.

摘要

目的

肥胖管理的重点是减轻体重以获得健康、心理和社会效益。然而,对照试验的结果并不能反映日常常规实践。因此,我们旨在调查在家中接受手术诱导减肥且未遵循方案进行随访的患者的减肥效果。

患者与方法

1980年至1997年间接受垂直束带胃成形术或胃旁路手术的患者符合条件。测量体重和身高。患者填写关于健康状况(诺丁汉健康量表(NHP))、心理症状(症状自评量表(SCL - 90 - R))、人格特质(荷兰人格问卷(DPQ))和饮食行为(荷兰饮食行为问卷(DEBQ))的问卷。

结果

在451例接受手术的患者中,可追踪到313名受试者的地址,其中236名(75%)同意参与。术后8.2(4.5)年,他们平均体重减轻了32.1(22.6)kg,超重部分减轻了45.2(29.3)%,约为术后17个月达到的最大体重减轻量的三分之二。除能量、睡眠和情绪反应外,男性的NHP和SCL - 90 - R符合正常值。女性在各个方面均与正常值不同,即使BMI<30 kg/m²的女性也未达到正常值。体重减轻与身体活动不便和疼痛呈负相关。与正常值相比,人格特质(DPQ)显示出更高的抱怨和支配性,以及更低的刻板性和自尊。女性在不适当性方面得分较高,在社交不适当性方面得分较低。饮食模式(DEBQ)主要表现为情绪化饮食和克制性饮食。选择效应量≥0.8标准差来反映具有统计学意义的结果的临床相关性。疼痛、睡眠、能量和活动障碍以及情绪化和克制性饮食被证明具有临床相关性。与近期接受手术的受试者相比,5年前接受手术的受试者表现出更高的敏感性、更高的不适当性和更低的社交不适当性。更克制的饮食模式与近期手术有关。

结论

即使在未严格遵循随访方案的患者中,手术诱导的体重减轻在长期来看也是令人满意的。健康、心理症状、人格特质和饮食行为与体重减轻及术后时间间隔有关,且未恢复到正常体重受试者的参考值。

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