Rubinowicz Maja, Piotrowski Robert, Nowobilski Roman
II Katedra Chorób Wewnetrznych Collegium Medicum Uniwersytetu Jagiellońskiego.
Pneumonol Alergol Pol. 2005;73(2):172-7.
The aim of this study was to evaluate some antropometric and clinical parameters in children with cystic fibrosis. Studies involved 34 patients with cystic fibrosis: 13 girls (38.24%) and 21 boys (61.76%) in the age of 6 to 18 (x +/- SD = 12 +/- 3,12 lat).
antropometric measurements (height, body weight, circumference of the chest), spirometry, 6 minute walkin test (6MWT), pulse oximetry had been measured for 4 consecutive years. Significant difference was found in dynamics of change of body weight in boys with cystic fibrosis in comparison with healthy boys in the age: 9-11 and 12-14 ( p< 0,001 and p< 0,03 respectively). Analogous differences were found in: dynamics of change of height in girls with cystic fibrosis in comparison to healthy girls in the age 12-14 (p<0.05) and in boys with cystic fibrosis in comparision to healthy boys in the age 9-11 (p< 0.001). Significant changes were observed in values of FEV1 and FVC EX in consecutive 4 years of observation (p<0.002) and p<0.002 respectively). Loss of saturation in subjects during 6 MWT was significant (p< 0,001); (x=2.69%). The mean of oxygen arterial blood saturation was 96.44% (initial level); 93.75% (post-test levels). There was correlation between the post-test level of saturation and circumference of the chest in girls with cystic fibrosis.
本研究的目的是评估囊性纤维化患儿的一些人体测量学和临床参数。研究涉及34例囊性纤维化患者:13名女孩(38.24%)和21名男孩(61.76%),年龄在6至18岁(x±标准差 = 12±3.12岁)。
连续4年测量人体测量学指标(身高、体重、胸围)、肺功能、6分钟步行试验(6MWT)、脉搏血氧饱和度。发现囊性纤维化男孩与同龄健康男孩相比,体重变化动态存在显著差异:9 - 11岁和12 - 14岁(分别为p < 0.001和p < 0.03)。在以下方面也发现了类似差异:12 - 14岁囊性纤维化女孩与健康女孩相比身高变化动态(p < 0.05),以及9 - 11岁囊性纤维化男孩与健康男孩相比(p < 0.001)。在连续4年的观察中,FEV1和FVC EX值有显著变化(分别为p < 0.002和p < 0.002)。6MWT期间受试者的饱和度下降显著(p < 0.001);(x = 2.69%)。动脉血氧饱和度平均值为96.44%(初始水平);93.75%(测试后水平)。囊性纤维化女孩测试后饱和度水平与胸围之间存在相关性。