Erdim Melike, Tezel Erdem, Biskin Nurdan
Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Marmara University, Tophanelioglu Caddesi, Altunizade, Uskudar, Istanbul, Turkey.
J Plast Reconstr Aesthet Surg. 2006;59(4):429-32. doi: 10.1016/j.bjps.2005.09.033.
Cholesterol crystal embolism is a multisystem disorder with a high mortality. It is usually seen following vascular surgery and long term anticoagulation therapy, but the diagnosis is often not considered. Skin manifestations are the first sign of cholesterol crystal embolism and recognition of the symptoms is a key element in early diagnosis and prevention of recurrences. We report a case who presented with acute renal failure, livedo reticularis and skin necrosis following angioplasty. Cutaneous biopsy revealed cholesterol crystals in the lumen of a vessel. Necrotic sites were treated with daily wound care and he was operated for reconstruction of tissue defects with cutaneous advancement flaps. One month after the operation healing was complete.
胆固醇结晶栓塞是一种死亡率很高的多系统疾病。它通常在血管手术后和长期抗凝治疗后出现，但往往未被考虑诊断。皮肤表现是胆固醇结晶栓塞的首发症状，识别这些症状是早期诊断和预防复发的关键因素。我们报告一例血管成形术后出现急性肾衰竭、网状青斑和皮肤坏死的病例。皮肤活检显示血管腔内有胆固醇结晶。坏死部位每天进行伤口护理，并采用皮肤推进皮瓣对组织缺损进行修复手术。术后一个月伤口完全愈合。
