Miller N S, Gold M S
Cornell University Medical College, New York Hospital-Cornell Medical Center, White Plains.
J Subst Abuse Treat. 1991;8(1-2):3-7. doi: 10.1016/0740-5472(91)90021-2.
Benzodiazepine use is prevalent. Moreover, benzodiazepine abuse, addiction, tolerance, and dependence occur commonly with benzodiazepine use. Confusion arises in assessing the nature and magnitude of benzodiazepine use and its consequences. Abuse, addiction, tolerance, and dependence occur in medical and nonmedical populations, but the studies do not clearly differentiate the benzodiazepine use between these two populations. The nonmedical use in medical populations is underestimated and underdiagnosed. The nonmedical use is also misdiagnosed in nonmedical populations as medical use. Clearer definitions and usage of the terms of abuse, addiction, tolerance, and dependence would result in accurate diagnosis and proper treatment of the disorders associated with benzodiazepine use, that is, anxiety and depressive disorders, alcoholism, and other drug addictions.
苯二氮䓬类药物的使用很普遍。此外，使用苯二氮䓬类药物时，滥用、成瘾、耐受性和依赖性也很常见。在评估苯二氮䓬类药物使用的性质、程度及其后果时会产生混淆。滥用、成瘾、耐受性和依赖性在医疗人群和非医疗人群中都有发生，但研究并未明确区分这两类人群中苯二氮䓬类药物的使用情况。医疗人群中的非医疗使用被低估且诊断不足。在非医疗人群中，非医疗使用也被误诊为医疗使用。对滥用、成瘾、耐受性和依赖性等术语进行更清晰的定义和使用，将有助于准确诊断和妥善治疗与苯二氮䓬类药物使用相关的疾病，即焦虑症、抑郁症、酗酒和其他药物成瘾。
