Morgan Craig, Dazzan Paola, Morgan Kevin, Jones Peter, Harrison Glynn, Leff Julian, Murray Robin, Fearon Paul
Division of Psychological Medicine, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK.
World Psychiatry. 2006 Feb;5(1):40-6.
In this paper we provide an overview of the design and the initial findings of the AESOP (Aetiology and Ethnicity in Schizophrenia and Other Psychoses) study. The AESOP study is a major multi-centre incidence and case-control study conducted in the UK. Its primary aim is to investigate the high rates of psychosis in African-Caribbean populations from the UK, and from this to shed light on the aetiology of psychosis in general. As the study has progressed, the wealth of data collected has allowed further questions to be addressed: for example, about determinants of duration of untreated psychosis. Initial findings relating to incidence rates and between-case comparisons are presented. Future planned analyses are outlined and details of a follow-up of the AESOP cohort and ongoing international collaborations are provided.
在本文中,我们概述了AESOP(精神分裂症及其他精神病的病因与种族)研究的设计及初步研究结果。AESOP研究是在英国开展的一项大型多中心发病率及病例对照研究。其主要目的是调查来自英国的非裔加勒比人群中精神病的高发病率,并据此深入了解精神病的总体病因。随着研究的推进,所收集的大量数据使得我们能够进一步探讨一些问题:例如,关于未治疗精神病持续时间的决定因素。本文呈现了与发病率及病例间比较相关的初步研究结果。概述了未来计划进行的分析,并提供了AESOP队列随访的详细信息以及正在进行的国际合作情况。