Crasta Julian A, Makhija Purnima, Kumar Karuna Ramesh, Sheriff Shameem
Department of Pathology, St. John's Medical College, Sarjapura Road, Bangalore-34.
Indian J Pathol Microbiol. 2005 Apr;48(2):170-2.
Lobular carcinoma is the most common pitfall in the cytodiagnosis of breast lesions. Of the cytological features described intracytoplasmic lumina are stressed by many authors as an important diagnostic feature. The present study aims at evaluating the importance of intracytoplasmic lumina in the cytodiagnosis of lobular carcinoma along with other cytological features. Fine needle aspirates from 11 cases of histologically proven classical lobular carcinomas of breast were reviewed. It was observed that the low cellularity, dispersed dyscohesive small cells, mild pleomorphism, nuclear moulding and Indian filing were the most important cytologic features which aid in the diagnosis of lobular carcinoma where as intracytoplasmic lumina were of little significance.
小叶癌是乳腺病变细胞诊断中最常见的误诊原因。在众多作者描述的细胞学特征中，胞质内管腔被强调为一项重要的诊断特征。本研究旨在评估胞质内管腔以及其他细胞学特征在小叶癌细胞诊断中的重要性。回顾了11例经组织学证实的乳腺经典小叶癌的细针穿刺抽吸物。观察到细胞数量少、分散的不黏附小细胞、轻度多形性、核镶嵌和印戒样排列是有助于诊断小叶癌的最重要细胞学特征，而胞质内管腔意义不大。
