Srinivasan R, Ranjini K, Vadhiraja B M
Department of Pathology, Kasturba Medical College, Manipal.
Indian J Pathol Microbiol. 2005 Apr;48(2):228-30.
Thyroglossal duct cyst is the most common developmental anomaly of the thyroid gland, presenting as a mid line neck swelling. Malignancy arising in them is a rare event, with papillary thyroid carcinoma being the commonest. Thyroglossal duct cyst carcinomas are usually asymptomatic and are not suspected preoperatively in most instances, hence the need for surgical excision and careful pathological examination of these cysts. We present a case of a 57 year old lady who underwent a Sistrunk procedure for the removal of thyroglossal duct cyst, which was responsible for a progressive mid line neck swelling of 2 months duration. The thyroid gland was normal. Histological examination of the excised cyst showed a papillary thyroid carcinoma arising in the thyroglossal duct cyst. Long term survival of patients with thyroglossal duct cyst carcinoma is excellent.
甲状舌管囊肿是甲状腺最常见的发育异常，表现为颈部中线肿胀。其中发生恶性肿瘤是罕见事件，最常见的是甲状腺乳头状癌。甲状舌管囊肿癌通常无症状，在大多数情况下术前不会被怀疑，因此需要对这些囊肿进行手术切除并仔细进行病理检查。我们报告一例57岁女性，她接受了Sistrunk手术以切除甲状舌管囊肿，该囊肿导致持续2个月的进行性颈部中线肿胀。甲状腺正常。切除囊肿的组织学检查显示甲状舌管囊肿内发生了甲状腺乳头状癌。甲状舌管囊肿癌患者的长期生存率良好。
