Bednarek Małgorzata, Majda-Stanisławska Ewa
Klinika Chorób Zakaźnych i Hepatologii Uniwersytetu Medycznego w Lodzi.
Przegl Epidemiol. 2006;60(1):49-52.
To estimate the incidence of MRSA strains in hospitalized children, the analysis of antibiotic treatment necessity and its effectiveness.
In 54 cases biological material obtained from hospitalized children revealed the culture of S. aureus, 22% of them were MRSA strains. Micro-organisms were cultured from throat swabs, faeces, purulent skin lesions, blood, cerebrospinal fluid. Antibiotic treatment was applied in 3 cases. Vancomycin (Edicin) was used as the first-choice option. Symptoms of drug intolerance was observed in all three cases after the first or the second dose, must have been immediately withdrawn.
MRSA strains are common in children population, they are not only nosocomial strains. Infections caused by S. aureus MRSA may result in life-threatening diseases. The generic formula of Vancomycin, that is used in Poland may cause serious side effects, which restricts narrow range of therapeutic options to eradicate MRSA strains.
评估住院儿童中耐甲氧西林金黄色葡萄球菌（MRSA）菌株的发生率，分析抗生素治疗的必要性及其有效性。
在54例从住院儿童获取的生物样本中培养出金黄色葡萄球菌，其中22%为MRSA菌株。微生物培养自咽拭子、粪便、脓性皮肤损伤、血液、脑脊液。3例接受了抗生素治疗。首选药物为万古霉素（依地霉素）。所有3例在首次或第二次给药后均出现药物不耐受症状，必须立即停药。
MRSA菌株在儿童群体中很常见，它们不仅是医院内感染菌株。由MRSA引起的感染可能导致危及生命的疾病。波兰使用的万古霉素通用配方可能会引起严重副作用，这限制了根除MRSA菌株的治疗选择范围。
