[1996年和2004年儿童尿路感染中ESBL菌株的患病率]

[Prevalence of ESBL strains in urinary tract infections in children in 1996 and 2004].

作者信息

Delińska-Galińska Anna, Kurlenda Julianna, Kozielska Ewa, Borkowska Anna, Luczak Grazyna, Plata-Nazar Katarzyna

机构信息

Klinika Pediatrii, Gastroenterologii i Onkologii Dzieciecej Akademii Medycznej w Gdańsku.

出版信息

Przegl Epidemiol. 2006;60(1):59-64.

PMID:16758740

Abstract

Ethiological agents in urinary tract infections and prevalence of bacterial strains producing extended spectrum of beta-lactamases isolated from urine of children with urinary tract infections were compared. Patients were hospitalized in Department of Pediatry, Pediatric Gastroenterology and Oncology of Medical University of Gdańsk in 1996 and 2004. Seventy bacterial strains isolated from urine in 1996 and 113 strains isolated in 2004 were analyzed. In both years Enterobacteriaceae were the most frequently encountered with Escherichia coli predominance. Proteus spp. (10.9%), Enterobacter spp. (7.1%), Klebsiella spp. (4.4%), and Enterococcus spp. (9.3%) were isolated rarely. Among bacteria isolated in 1996 there were no ESBL strains while in 2004 ESBL strains accounted for 11.5% of all urinary bacteria. Klebsiella oxytoca (25%) and Klebsiella pneumaniae (20%) produced ESBL most frequently. ESBL production was less frequent in Escherichia coli (13.2%) and Proteus mirablilis (10%). In conclusion, among bacteria isolated from urine of children with urinary tract infections G(-) strains producing ESBL were encountered only in recent years.

摘要

比较了尿路感染的病原体以及从尿路感染患儿尿液中分离出的产超广谱β-内酰胺酶细菌菌株的流行情况。患者于1996年和2004年在格但斯克医科大学儿科、儿科胃肠病学和肿瘤学系住院。分析了1996年从尿液中分离出的70株细菌菌株和2004年分离出的113株菌株。在这两年中，肠杆菌科最为常见，以大肠杆菌为主。变形杆菌属（10.9%）、肠杆菌属（7.1%）、克雷伯菌属（4.4%）和肠球菌属（9.3%）分离较少。1996年分离出的细菌中没有产ESBL菌株，而2004年产ESBL菌株占所有尿液细菌的11.5%。产酸克雷伯菌（25%）和肺炎克雷伯菌（20%）产ESBL最为常见。大肠杆菌（13.2%）和奇异变形杆菌（10%）中产ESBL的情况较少。总之，在从尿路感染患儿尿液中分离出的细菌中，产ESBL的革兰氏阴性菌株仅在近年来才出现。