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伴有红系造血低下的骨髓增生异常综合征:一种罕见且独特的临床病理实体——两例报告

Myelodysplastic syndrome with erythroid hypoplasia: a rare and distinct clincopathological entity--a report of two cases.

作者信息

Kumar Vijay, Dash Sumitra

机构信息

Department of Haematology, PGIMER Chandigarh.

出版信息

Indian J Pathol Microbiol. 2005 Jan;48(1):36-7.

PMID:16758786
Abstract

Erythroid hypoplasia in myelodysplastic syndrome (MDS) happens to be a rare association and is being recognized as a distinct clinico pathological entity. We report here two such cases diagnosed as Refractory anaemia (RA) and Refractory anaemia with excess blast (RAEB) who had marked suppression of the erythroid cell lines. Both patients presented with severe transfusion dependent anaemia. Recognition of these cases is important as alternative modalities of treatment such as immunosuppressives may be considered for these patients.

摘要

骨髓增生异常综合征(MDS)中的红系造血低下实属罕见关联,正被视作一种独特的临床病理实体。我们在此报告两例被诊断为难治性贫血(RA)和伴有过多原始细胞的难治性贫血(RAEB)的病例,这两例患者的红系细胞系均受到显著抑制。两名患者均表现为严重的依赖输血的贫血。认识到这些病例很重要,因为对于这些患者可考虑采用免疫抑制剂等替代治疗方式。

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