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克伦特罗对大鼠生长的影响。

The influence of clenbuterol on growth in rats.

作者信息

Peréz-Llamas F, Zamora S

机构信息

Department of Physiology and Pharmacology, University of Murcia, Spain.

出版信息

Comp Biochem Physiol A Comp Physiol. 1991;99(1-2):241-4. doi: 10.1016/0300-9629(91)90266-f.

DOI:10.1016/0300-9629(91)90266-f
PMID:1675953
Abstract
  1. The influence was studied of a beta 2-agonist, clenbuterol, on mean gain of body weight, feed efficiency and growth of muscle tissue in female Wistar rats of three different weights (70, 150 and 200 g). 2. Clenbuterol significantly increases mean gain of body weight and feed efficiency in all the studies realised, but much more effectively in animals of greater age/weight (200 g). 3. In addition, it favours protein deposition in muscle, given that it increases significantly (P less than 0.001) the muscle/body weight ratio in all of the experiments.
摘要
  1. 研究了β2-激动剂克伦特罗对三种不同体重(70、150和200克)雌性Wistar大鼠体重平均增加量、饲料效率和肌肉组织生长的影响。2. 在所有开展的研究中,克伦特罗均显著增加体重平均增加量和饲料效率,但在年龄/体重较大的动物(200克)中效果更显著。3. 此外,它有利于肌肉中的蛋白质沉积,因为在所有实验中它均显著提高(P<0.001)肌肉/体重比。

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1
The influence of clenbuterol on growth in rats.克伦特罗对大鼠生长的影响。
Comp Biochem Physiol A Comp Physiol. 1991;99(1-2):241-4. doi: 10.1016/0300-9629(91)90266-f.
2
Influence of dietary protein level on growth: effect of clenbuterol.日粮蛋白质水平对生长的影响:克伦特罗的作用
Comp Biochem Physiol A Comp Physiol. 1991;99(4):671-5. doi: 10.1016/0300-9629(91)90148-6.
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Stimulation of muscle growth by clenbuterol: lack of effect on muscle protein biosynthesis.
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Effect of clenbuterol on growth and body composition during food restriction in rats.
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Effects of bovine pituitary growth hormone alone or in combination with the beta-agonist clenbuterol on muscle growth and composition in veal calves.单独使用牛垂体生长激素或与β-激动剂克伦特罗联合使用对犊牛肌肉生长和组成的影响。
Br J Nutr. 1990 May;63(3):535-45. doi: 10.1079/bjn19900140.
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Comparison of the effects of salbutamol and clenbuterol on skeletal muscle mass and carcass composition in senescent rats.沙丁胺醇与克伦特罗对衰老大鼠骨骼肌质量和胴体组成影响的比较。
Metabolism. 1994 Sep;43(9):1119-25. doi: 10.1016/0026-0495(94)90054-x.
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Anabolic beta-2-agonist clenbuterol fails to modify muscle atrophy due to femur fracture.
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Clenbuterol increases the expression of myogenin but not myoD in immobilized rat muscles.
Am J Physiol. 1997 May;272(5 Pt 1):E941-4. doi: 10.1152/ajpendo.1997.272.5.E941.
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Effects of clenbuterol and propranolol on muscle mass. Evidence that clenbuterol stimulates muscle beta-adrenoceptors to induce hypertrophy.克伦特罗和普萘洛尔对肌肉质量的影响。有证据表明克伦特罗刺激肌肉β-肾上腺素能受体以诱导肥大。
Biochem J. 1989 Dec 1;264(2):573-9. doi: 10.1042/bj2640573.
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Clenbuterol, a beta agonist, induces growth in innervated and denervated rat soleus muscle via apparently different mechanisms.克仑特罗,一种β激动剂,通过明显不同的机制诱导去神经支配和未去神经支配的大鼠比目鱼肌生长。
Biosci Rep. 1987 Jun;7(6):525-32. doi: 10.1007/BF01116510.

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Effects of clenbuterol and ICI118551, a selective beta 2-antagonist, on the growth of skeletal muscle of suckling rats.克伦特罗和选择性β2拮抗剂ICI118551对乳鼠骨骼肌生长的影响。
Pflugers Arch. 1995 Dec;431(2):237-43. doi: 10.1007/BF00410196.