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日粮蛋白质水平对生长的影响:克伦特罗的作用

Influence of dietary protein level on growth: effect of clenbuterol.

作者信息

Peréz-Llamas F, Sastre J F, Zamora S

机构信息

Department of Physiology and Pharmacology, University of Murcia, Spain.

出版信息

Comp Biochem Physiol A Comp Physiol. 1991;99(4):671-5. doi: 10.1016/0300-9629(91)90148-6.

DOI:10.1016/0300-9629(91)90148-6
PMID:1679705
Abstract
  1. The influence has been studied of a beta-agonist, clenbuterol, on body weight increase, feed efficiency and muscular tissue growth in Wistar rats of two different weights (70 and 200 g) fed with a diet of differing protein levels (4, 10 and 15%). 2. Treatment with clenbuterol had a negative influence on body growth and feed efficiency when the animals were fed with low protein diets (4%). 3. With a higher protein content (10 and 15%), the situation changed completely, and these indices increased, with a relationship appearing between these changes, the agonist dose and the animal's age. 4. In all the experiments clenbuterol improved muscle/body ratio significantly (P less than 0.001). The favourable effect of clenbuterol on muscle growth is due to a specific increase in protein deposition and not to changes in the water content of muscular tissue, even though these changes may be produced.
摘要
  1. 研究了β-激动剂克伦特罗对两种不同体重(70克和200克)的Wistar大鼠体重增加、饲料效率和肌肉组织生长的影响,这些大鼠饲喂不同蛋白质水平(4%、10%和15%)的日粮。2. 当动物饲喂低蛋白日粮(4%)时,克伦特罗处理对身体生长和饲料效率有负面影响。3. 蛋白质含量较高(10%和15%)时,情况完全改变,这些指标增加,这些变化、激动剂剂量与动物年龄之间呈现出一种关系。4. 在所有实验中,克伦特罗均显著提高了肌肉/身体比例(P<0.001)。克伦特罗对肌肉生长的有利作用归因于蛋白质沉积的特异性增加,而非肌肉组织水分含量的变化,尽管可能会产生这些变化。

相似文献

1
Influence of dietary protein level on growth: effect of clenbuterol.日粮蛋白质水平对生长的影响:克伦特罗的作用
Comp Biochem Physiol A Comp Physiol. 1991;99(4):671-5. doi: 10.1016/0300-9629(91)90148-6.
2
The influence of clenbuterol on growth in rats.克伦特罗对大鼠生长的影响。
Comp Biochem Physiol A Comp Physiol. 1991;99(1-2):241-4. doi: 10.1016/0300-9629(91)90266-f.
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[Effect of a beta-agonist and a beta-agonist/beta-antagonist combination on muscle growth, body composition and protein metabolism in rats].[β-激动剂及β-激动剂/β-拮抗剂组合对大鼠肌肉生长、身体成分及蛋白质代谢的影响]
Arch Tierernahr. 1993;45(3):211-25. doi: 10.1080/17450399309386101.
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The digestive and metabolic utilization of the dietary protein: effect of clenbuterol and protein level.膳食蛋白质的消化和代谢利用:克伦特罗和蛋白质水平的影响。
Arch Int Physiol Biochim Biophys. 1992 Jan-Feb;100(1):27-31. doi: 10.3109/13813459209035255.
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Clenbuterol-induced muscle growth: investigation of possible mediation by insulin.克仑特罗诱导的肌肉生长:胰岛素可能介导作用的研究
Am J Physiol. 1987 Oct;253(4 Pt 1):E370-5. doi: 10.1152/ajpendo.1987.253.4.E370.
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Effect of clenbuterol on recovery of muscle mass and carcass protein content following dietary protein depletion in young and old rats.克伦特罗对幼龄和老龄大鼠饮食性蛋白质缺乏后肌肉量和胴体蛋白质含量恢复的影响。
J Gerontol. 1994 Jul;49(4):B162-8. doi: 10.1093/geronj/49.4.b162.
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Effect of a selective beta 2-adrenergic agonist (clenbuterol) on energy balance and body composition in normal and protein deficient rats.选择性β2-肾上腺素能激动剂(克伦特罗)对正常及蛋白质缺乏大鼠能量平衡和身体组成的影响。
Biosci Rep. 1987 Dec;7(12):933-40. doi: 10.1007/BF01122126.
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Influence of clenbuterol on the protein digestibility and on nitrogen balance in rats.克伦特罗对大鼠蛋白质消化率及氮平衡的影响。
Comp Biochem Physiol Comp Physiol. 1992 Mar;101(3):619-23. doi: 10.1016/0300-9629(92)90517-t.
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Stimulation of muscle growth by clenbuterol: lack of effect on muscle protein biosynthesis.
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Effects of the beta 2-adrenoceptor agonist, clenbuterol, on muscle atrophy due to food deprivation in the rat.
Metabolism. 1990 Jun;39(6):647-50. doi: 10.1016/0026-0495(90)90034-a.

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Clenbuterol: a medal in tablet form?克仑特罗:片状的奖牌?
Br J Sports Med. 1993 Jun;27(2):141. doi: 10.1136/bjsm.27.2.141.