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婴儿痉挛症:小发作,大后果。

Infantile spasms: little seizures, BIG consequences.

机构信息

Division of Pediatric Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

出版信息

Epilepsy Curr. 2006 May-Jun;6(3):63-9. doi: 10.1111/j.1535-7511.2006.00100.x.

DOI:10.1111/j.1535-7511.2006.00100.x
PMID:16761063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1464162/
Abstract

Infantile spasms is one of the "catastrophic childhood epilepsies" because of the difficulty in controlling seizures and the association with mental retardation. However, early recognition, a careful diagnostic evaluation, and proper treatment may allow some children to attain seizure control and to achieve a normal, or at least much improved, level of development. Thus, there is the opportunity to have an important impact in the lives of these unfortunate children and their families.

摘要

婴儿痉挛症是“灾难性婴幼儿癫痫”之一,因为其难以控制癫痫发作且与智力迟钝有关。然而,早期识别、仔细的诊断评估和适当的治疗可能使一些儿童获得癫痫控制,并实现正常,或至少大大改善,的发育水平。因此,有机会对这些不幸的儿童及其家庭的生活产生重要影响。

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Infantile spasms: little seizures, BIG consequences.婴儿痉挛症:小发作,大后果。
Epilepsy Curr. 2006 May-Jun;6(3):63-9. doi: 10.1111/j.1535-7511.2006.00100.x.
2
Catastrophic epilepsy in childhood.儿童灾难性癫痫
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Diagnosing infantile spasms: Accuracy of the internet.诊断婴儿痉挛症:互联网的准确性。
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Infantile spasms in children with Down syndrome.唐氏综合征患儿的婴儿痉挛症
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Surgery for the treatment of medically intractable infantile spasms: a cautionary case.手术治疗药物难治性婴儿痉挛症:一则警示案例。
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Risk factors of infantile spasms compared with other seizures in children under 2 years of age.与2岁以下儿童的其他癫痫发作相比,婴儿痉挛症的风险因素。
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Simultaneous infantile spasms and partial seizures.婴儿痉挛症与部分性发作同时出现。
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本文引用的文献

1
Surgery for symptomatic infant-onset epileptic encephalopathy with and without infantile spasms.针对有或无婴儿痉挛症的症状性婴儿期起病的癫痫性脑病的手术治疗。
Neurology. 2005 Feb 22;64(4):746-50. doi: 10.1212/01.WNL.0000151970.29205.70.
2
[Findings in 21 cases of Gibbs' hypsarrhythmia; spectacular effectiveness of ACTH].[21例吉布斯高度节律失调症的研究结果;促肾上腺皮质激素的显著疗效]
Acta Neurol Psychiatr Belg. 1958 Feb;58(2):130-41.
3
Topiramate: efficacy and tolerability in children according to epilepsy syndromes.托吡酯:根据癫痫综合征评估其在儿童中的疗效和耐受性
Epilepsy Res. 2003 Mar;53(3):225-32. doi: 10.1016/s0920-1211(03)00028-7.
4
Classification of infantile seizures: implications for identification and treatment of inborn errors of metabolism.婴儿癫痫发作的分类:对先天性代谢缺陷的识别与治疗的意义。
J Child Neurol. 2002 Dec;17 Suppl 3:3S3-7; discussion 3S8.
5
Benign familial infantile seizures: further delineation of the syndrome.良性家族性婴儿惊厥:综合征的进一步界定。
J Child Neurol. 2002 Sep;17(9):696-9. doi: 10.1177/088307380201700909.
6
Ictal pattern of EEG and muscular activation in symptomatic infantile spasms: a videopolygraphic and computer analysis.症状性婴儿痉挛症的脑电图发作模式与肌肉激活:视频多导记录及计算机分析
Epilepsia. 2002 Dec;43(12):1559-63. doi: 10.1046/j.1528-1157.2002.15302.x.
7
Low-dose lamotrigine in West syndrome.低剂量拉莫三嗪治疗韦斯特综合征
Epilepsy Res. 2002 Sep;51(1-2):199-200. doi: 10.1016/s0920-1211(02)00100-6.
8
Clinical and electrographic features of epileptic spasms persisting beyond the second year of life.癫痫性痉挛持续至生命第二年之后的临床和脑电图特征。
Epilepsia. 2002 Jun;43(6):623-30.
9
West's syndrome (infantile spasms). Clinical description and diagnosis.韦斯特综合征(婴儿痉挛症)。临床描述与诊断。
Adv Exp Med Biol. 2002;497:33-50.
10
Efficacy of the ketogenic diet for infantile spasms.生酮饮食对婴儿痉挛症的疗效。
Pediatrics. 2002 May;109(5):780-3. doi: 10.1542/peds.109.5.780.