Jain Deepali, Joshi K, Jindal S K
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Indian J Pathol Microbiol. 2005 Jul;48(3):399-402.
Although precursor lesions of bronchogenic squamous cell carcinoma are well documented, the preinvasive lesions of pulmonary adenocarcinoma are seen very rarely. It has been hypothesized that there is a stepwise progression of alveolar epithelial hyperplasia to atypical alveolar hyperplasia and subsequently to malignancy in the pathogenesis of peripheral adenocarcinoma of the lung. In the present paper we would like to share our experience of two cases of pulmonary adenocarcinoma with their precursor lesions in the form of atypical alveolar hyperplasia.
虽然支气管源性鳞状细胞癌的前驱病变已有充分记录，但肺腺癌的浸润前病变却极为罕见。据推测，在肺外周腺癌的发病机制中，存在从肺泡上皮增生到非典型肺泡增生，随后发展为恶性肿瘤的逐步进展过程。在本文中，我们希望分享两例肺腺癌及其前驱病变——非典型肺泡增生的病例经验。
