Farrier S L, Farrier J N, Smart M K, Nash E S
Adult Dental Health, University of Wales Dental Hospital, Cardiff, Wales, UK.
J Oral Pathol Med. 2006 Jul;35(6):332-7. doi: 10.1111/j.1600-0714.2006.00384.x.
There is considerable variation in the clinical presentation, behaviour and radiological appearance of central giant cell granulomas (CGCGs), for which multiple treatment modalities have been suggested.
A 10-year retrospective review of the clinical presentation, radiological features and treatment received was undertaken.
The cohort of patients included six males and three females, with an age range of 7-61 years. Six lesions were in the mandible and three in the maxilla. Eight lesions presented with swelling, three in relation to teeth. One case was an incidental finding. Six cases were confined within the cortical plates, one involved soft tissue. Radiological presentation was diverse, but within the existing confines of CGCGs. With one exception, primary treatment was surgical resection with excisional curettage of the remaining bone; to date, none have recurred.
Diagnosis relies on correct interpretation of clinical, radiographical and histopathological data. Alternative treatments are worthy of consideration, although surgical excision remains the treatment of choice.
中央巨细胞肉芽肿（CGCG）的临床表现、行为和影像学表现存在很大差异，针对其提出了多种治疗方式。
对临床表现、影像学特征及接受的治疗进行了为期10年的回顾性研究。
患者队列包括6名男性和3名女性，年龄范围为7至61岁。6处病损位于下颌骨，3处位于上颌骨。8处病损表现为肿胀，3处与牙齿有关。1例为偶然发现。6例局限于皮质板内，1例累及软组织。影像学表现多样，但在CGCG现有的范围内。除1例例外，主要治疗方法是手术切除并刮除剩余骨质；迄今为止，无一例复发。
诊断依赖于对临床、影像学和组织病理学数据的正确解读。尽管手术切除仍是首选治疗方法，但其他治疗方法也值得考虑。
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