Daryani Deepak, Gopakumar R
Department of Oral Medicine and Radiology, Syamala Reddy Dental College and Research Centre, Bangalore, India.
Contemp Clin Dent. 2011 Jul;2(3):249-52. doi: 10.4103/0976-237X.86483.
Central giant cell granulomas are non-neoplastic lesions of unknown etiology. They affect females more than males with the mandibular anterior region being the most common site of occurrence. Clinically central giant cell granulomas present as asymptomatic, expansile swellings causing deviation of associated teeth. Radiologically they usually presents as multilocular lesions causing expansion or perforation of cortical bone. Central giant cell granulomas are usually confused as other lesions both clinically and radiologically, and a definitive diagnosis can be made only histologically. We report here a rare case of central giant cell granuloma in association with congenitally missing tooth which was misdiagnosed to be an adenomatoid odontogenic tumor both clinically and radiologically. This case report also highlights yet another unique presentation of central giant cell granulomas that is in association with a congenitally missing maxillary lateral incisor.
中央巨细胞肉芽肿是病因不明的非肿瘤性病变。女性比男性更易受累，下颌前部区域是最常见的发病部位。临床上，中央巨细胞肉芽肿表现为无症状的膨胀性肿物，导致相关牙齿移位。放射学上，它们通常表现为多房性病变，引起皮质骨膨胀或穿孔。中央巨细胞肉芽肿在临床和放射学上通常与其他病变相混淆，只有通过组织学检查才能做出明确诊断。我们在此报告一例罕见的中央巨细胞肉芽肿合并先天性缺牙病例，该病例在临床和放射学上均被误诊为腺样牙源性肿瘤。本病例报告还突出了中央巨细胞肉芽肿与先天性上颌侧切牙缺失相关的另一种独特表现。
