Chen Zu-ji
Zhonghua Yan Ke Za Zhi. 2006 Apr;42(4):292-5.
Choosing appropriate drug delivery system can apparently improve drug efficacy, prolong action time and decrease adverse reaction. In recent years, with the progress of macromolecule chemistry, the research of ocular drug delivery system has been developed rapidly. The present article reviews the progress of ocular drug delivery system and its development in our country. This article also discusses how to exploit the macromolecule polymer material with independence intellectual property rights, and how to promote the studies of intraocular pharmacokinetics and ocular toxicology about new ocular drug delivery system.
选择合适的药物递送系统显然可以提高药物疗效、延长作用时间并减少不良反应。近年来,随着高分子化学的进展,眼部药物递送系统的研究迅速发展。本文综述了眼部药物递送系统的进展及其在我国的发展情况。本文还讨论了如何开发具有自主知识产权的高分子聚合物材料,以及如何推动新型眼部药物递送系统的眼内药代动力学和眼毒理学研究。