Lu Ning, Yang Qing-song, Ma Kai, Zhou Hai-ying, Xiong Ying, Yan Wei
Tongren Ophthalmic Center, Capital University of Medical Science, Beijing 100730, China.
Zhonghua Yan Ke Za Zhi. 2006 Apr;42(4):326-9.
In this study, the clinical effect of the Nd: YAG laser embolysis on branch retinal artery occlusion was evaluated.
A fundus contact lens was used to focus the Nd: YAG laser on the embolus within the retinal arteriole. 0.8 to 0.9 mJ of laser pulse was delivered directly to the embolus. Fundus photographs were taken before and immediately after the treatment. Follow-up time ranged from 2 weeks to 4 months, average about 7 weeks. Seven cases received the treatment, including 5 male and 2 female patients. Age of those cases ranged from 49 to 73, average 61 years. The duration of the disease ranged from 1 to 60 days, average 13 days.
Before treatment, visual acuity ranged from 0.06 to 0.8. Embolus can be detected in all the 7 cases. After treatment, all the cases showed immediate recovery of blood flow in the occluded arteriole both in fundus examination and fundus fluorescein angiography. The vision in the patients was improved in the follow-up. Visual acuity ranged from 0.2 approximately 1.0. In most cases, visual field defect still existed in the ischemic area. Complications included local retinal hemorrhages in some cases and vitreous hemorrhage, but those hemorrhages were gradually absorbed and did not affect the final visual prognosis.
Nd: YAG laser embolysis for branch retinal artery occlusion is an effective treatment and the treatment is relatively safe.
本研究评估了钕钇铝石榴石（Nd:YAG）激光栓子溶解术治疗视网膜分支动脉阻塞的临床效果。
使用眼底接触镜将Nd:YAG激光聚焦于视网膜小动脉内的栓子上。将0.8至0.9毫焦的激光脉冲直接作用于栓子。在治疗前和治疗后即刻拍摄眼底照片。随访时间为2周至4个月，平均约7周。7例患者接受了该治疗，其中男性5例，女性2例。这些患者的年龄在49至73岁之间，平均61岁。病程为1至60天，平均13天。
治疗前，视力范围为0.06至0.8。所有7例患者均能检测到栓子。治疗后，眼底检查和眼底荧光血管造影显示所有病例阻塞的小动脉均立即恢复血流。随访期间患者视力有所改善。视力范围约为0.2至1.0。大多数病例中，缺血区域仍存在视野缺损。并发症包括部分病例出现局部视网膜出血和玻璃体积血，但这些出血逐渐吸收，未影响最终视力预后。
Nd:YAG激光栓子溶解术治疗视网膜分支动脉阻塞是一种有效的治疗方法，且该治疗相对安全。
