Kang Taek Won, Lee Kyung Hwa, Piao Cheng Zhe, Yun Ki Jung, Joo Hee Jae, Park Kwang Sung, Choi Yoo Duk, Juhng Sang Woo, Choi Chan
Department of Urology, Chonnam National University Medical School, #5 Hak-dong, Dong-gu, Gwangju, 501-749, Republic of Korea.
J Infect. 2007 Feb;54(2):e69-73. doi: 10.1016/j.jinf.2006.04.005. Epub 2006 Jun 8.
Xanthogranulomatous epididymitis is an uncommon but benign process, characterized by tissue destruction and the accumulation of abundant foamy macrophages mixed with lymphocytes and plasma cells. The pathogens generally found to cause xanthogranulomatous inflammation have been Proteus and E. coli. We identified such a pathogen by sequencing divergent regions of 16S rRNA, followed by pathogen-specific-PCR using alr, ipaH, ial, and iuc primer pairs in DNA microdissected from an H&E stained slide. We report here three cases of xanthogranulomatous epididymitis caused by E. coli.
黄色肉芽肿性附睾炎是一种罕见但良性的病变，其特征是组织破坏以及大量泡沫状巨噬细胞与淋巴细胞和浆细胞混合积聚。通常发现可引起黄色肉芽肿性炎症的病原体为变形杆菌和大肠杆菌。我们通过对16S rRNA的不同区域进行测序来鉴定此类病原体，随后在从苏木精-伊红（H&E）染色切片中显微切割的DNA中，使用alr、ipaH、ial和iuc引物对进行病原体特异性聚合酶链反应（PCR）。我们在此报告三例由大肠杆菌引起的黄色肉芽肿性附睾炎病例。
