Warnock James N, Al-Rubeai Mohamed
Department of Agricultural and Biological Engineering, Mississippi State University, Mississippi State, 39762, USA.
Biotechnol Appl Biochem. 2006 Jul;45(Pt 1):1-12. doi: 10.1042/BA20050233.
The demand for biopharmaceutical products is set to see a significant increase over the next few years. As a consequence, the processes used to produce these products must be able to meet market requirements. The present paper reviews the current technologies available for animal cell culture and highlights the advantages and disadvantages of each method, while also providing details of recent case studies. Processes are described for both suspension and anchorage-dependent cell lines.
未来几年，对生物制药产品的需求预计将大幅增长。因此，用于生产这些产品的工艺必须能够满足市场需求。本文综述了目前可用于动物细胞培养的技术，强调了每种方法的优缺点，同时还提供了近期案例研究的详细信息。文中描述了悬浮细胞系和贴壁依赖性细胞系的培养过程。
