Fang Jing, Alderman Michael H
The Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Am J Cardiol. 2006 Jun 15;97(12):1722-6. doi: 10.1016/j.amjcard.2006.01.032. Epub 2006 Apr 21.
Women are less likely to undergo revascularization after acute myocardial infarction (AMI). We assessed whether this was due to patterns of hospital admission or less frequent revascularization even when resources are available. Using New York City hospital discharge records from 1995 to 2002, we determined revascularization rates for patients who were hospitalized for AMI. Rates of admission to hospitals capable of revascularizing and revascularization use were assessed by gender. Odds ratios of admission and procedure use were determined after adjusting for sociodemographic and clinical characteristics and accounting for availability of revascularization in neighborhoods of residence. Of 93,978 patients with AMI (43.7% women), 27% were revascularized (32% and 20% for men and women, respectively, p <0.001). Moreover, women were less likely than men to be admitted to hospitals capable of revascularization (45% vs 52%, p <0.001) and to undergo revascularization (54% vs 60%, p <0.001) when admitted to capable hospitals. These differences were similar for residents of neighborhoods with or without revascularization services. Odds ratios for men versus women were 1.22 (95% confidence interval 1.18 to 1.26) for admission to revascularizing hospitals and 1.28 (95% confidence interval 1.22 to 1.34) for using revascularization among patients in revascularization hospitals. The in-hospital mortality advantage of men over women persisted after revascularization (9.6% vs 14.5%). In conclusion, less revascularization after AMI among women was associated with less frequent admission to hospitals capable of revascularization and less frequent revascularization even when admitted to performing hospitals. However, improving revascularization among women does not eliminate the gender disparity of in-hospital death after AMI.
急性心肌梗死(AMI)后,女性接受血运重建的可能性较低。我们评估了这是否是由于住院模式所致,还是即便有可用资源时女性接受血运重建的频率也较低。利用1995年至2002年纽约市医院出院记录,我们确定了因AMI住院患者的血运重建率。按性别评估了能够进行血运重建的医院的入院率和血运重建的使用率。在调整社会人口统计学和临床特征并考虑居住社区血运重建的可及性后,确定了入院和手术使用的比值比。在93978例AMI患者中(43.7%为女性),27%接受了血运重建(男性和女性分别为32%和20%,p<0.001)。此外,女性比男性更不可能被收治到能够进行血运重建的医院(45%对52%,p<0.001),并且在被收治到有能力的医院时接受血运重建的可能性也更低(54%对60%,p<0.001)。对于有或没有血运重建服务的社区居民,这些差异相似。在能够进行血运重建的医院入院方面,男性与女性的比值比为1.22(95%置信区间1.18至1.26),在血运重建医院中使用血运重建方面,男性与女性的比值比为1.28(95%置信区间1.22至1.34)。血运重建后,男性在院内死亡率方面相对于女性的优势依然存在(9.6%对14.5%)。总之,AMI后女性血运重建较少与入住能够进行血运重建的医院频率较低以及即便入住有能力进行血运重建的医院时血运重建频率较低有关。然而,改善女性的血运重建并不能消除AMI后院内死亡的性别差异。